EC Explorer

4.2.3.127

β-copaene synthase

(2E,6E)-farnesyl diphosphate = β-copaene + diphosphate

cop4

(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, β-copaene-forming)

Isolated from the fungus Coprinus cinereus. The enzyme also forms (+)-δ-cadinene, β-cubebene, (+)-sativene and traces of several other sequiterpenoids [1-3]. β-Copaene is formed in the presence of Mg²⁺ but not Mn²⁺ [2]. See EC 4.2.3.13, (+)-δ-cadinene synthase, EC 4.2.3.128, β-cubebene synthase, and EC 4.2.3.129, (+)-sativene synthase.

created 2012