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EC 3.5.1.123 Details
show Brenda entryEC number
3.5.1.123
Accepted name
γ-glutamylanilide hydrolase
Reaction
N5-phenyl-L-glutamine + H2O = L-glutamate + aniline
Other name(s)
atdA2 (gene name)
Systematic name
N5-phenyl-L-glutamine amidohydrolase
Comment
The enzyme, characterized from the bacterium Acinetobacter sp. YAA, catalyses the opposite reaction from that catalysed by EC 6.3.1.18, γ-glutamylanilide synthase, which is part of an aniline degradation pathway. Its purpose is likely to maintain a low concentration of N5-phenyl-L-glutamine, which is potentially toxic.
History
created 2016
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1 Oxidoreductases
1.1.1 With NAD+ or NADP+ as acceptor
1.8.4.1 glutathione—homocystine transhydrogenase
