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EC 1.8.2.2 Details
show Brenda entryEC number
1.8.2.2
Accepted name
thiosulfate dehydrogenase
Reaction
2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c
Other name(s)
tsdA (gene name),
tetrathionate synthase,
thiosulfate oxidase,
thiosulfate-oxidizing enzyme,
thiosulfate-acceptor oxidoreductase
Systematic name
thiosulfate:ferricytochrome-c oxidoreductase
CAS registry number
9076-88-4
Comment
The enzyme catalyses the reversible formation of a sulfur-sulfur bond between the sulfane atoms of two thiosulfate molecules, yielding tetrathionate and releasing two electrons. In many bacterial species the enzyme is a diheme c-type cytochrome. In a number of organisms, including Thiomonas intermedia and Sideroxydans lithotrophicus, a second diheme cytochrome (TsdB) acts as the electron acceptor. However, some organisms, such as Allochromatium vinosum, lack TsdB. The electron acceptor in these organisms may be the high-potential iron-sulfur protein (HiPIP).
History
created 1990
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1 Oxidoreductases
1.1.1 With NAD+ or NADP+ as acceptor
1.1.3.1 created 1961, deleted 1984 1.1.3.25 created 1986, deleted 2005 1.1.3.26 created 1989, deleted 2002 1.1.3.31 created 1992, deleted 2003 1.1.3.32 created 1999, deleted 2002 1.1.3.33 created 1999, deleted 2002 1.1.3.34 created 1999, deleted 2002 1.1.3.35 created 1999, deleted 2002 1.1.3.36 created 1999, deleted 2002
