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EC 3.6.4.13 Details
show Brenda entryEC number
3.6.4.13
Accepted name
RNA helicase
Reaction
ATP + H2O = ADP + phosphate
Other name(s)
CSFV NS3 helicase,
DBP2,
DbpA,
DDX17,
DDX25,
DDX3,
DDX3X,
DDX3Y,
DDX4,
DDX5,
DEAD-box protein DED1,
DEAD-box RNA helicase,
DEAH-box protein 2,
DEAH-box RNA helicase,
DED1,
Dex(H/D) RNA helicase,
EhDEAD1,
EhDEAD1 RNA helicase,
eIF4A helicase,
KOKV helicase,
Mtr4p,
nonstructural protein 3 helicase,
NPH-II,
RHA,
RNA helicase A,
RNA helicase DDX3,
RNA helicase Hera,
RNA-dependent ATPase,
TGBp1 NTPase/helicase domain,
VRH1,
GRTH/DDX25
Systematic name
ATP phosphohydrolase (RNA helix unwinding)
Comment
RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. Some of them unwind RNA with a 3′ to 5′ polarity [3], other show 5′ to 3′ polarity [8]. Some helicases unwind DNA as well as RNA [7,8]. May be identical with EC 3.6.4.12 (DNA helicase).
History
created 2009
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1 Oxidoreductases
1.1.1 With NAD+ or NADP+ as acceptor
1.1.3.1 created 1961, deleted 1984 1.1.3.25 created 1986, deleted 2005 1.1.3.26 created 1989, deleted 2002 1.1.3.31 created 1992, deleted 2003 1.1.3.32 created 1999, deleted 2002 1.1.3.33 created 1999, deleted 2002 1.1.3.34 created 1999, deleted 2002 1.1.3.35 created 1999, deleted 2002 1.1.3.36 created 1999, deleted 2002 1.1.5.1 created 1983, deleted 2002
