EC Explorer
[browse EC tree] - [search]
EC 4.2.1.116 Details
show Brenda entryEC number
4.2.1.116
Accepted name
3-hydroxypropionyl-CoA dehydratase
Reaction
3-hydroxypropanoyl-CoA = acryloyl-CoA + H2O
Other name(s)
3-hydroxypropionyl-CoA hydro-lyase,
3-hydroxypropanoyl-CoA dehydratase
Systematic name
3-hydroxypropanoyl-CoA hydro-lyase
Comment
Catalyses a step in the 3-hydroxypropanoate/4-hydroxybutanoate cycle, an autotrophic CO2 fixation pathway found in some thermoacidophilic archaea [1]. The enzyme from Metallosphaera sedula acts nearly equally as well on (S)-3-hydroxybutanoyl-CoA but not (R)-3-hydroxybutanoyl-CoA [2].
History
created 2009
back to topEC Tree
1 Oxidoreductases
1.1.1 With NAD+ or NADP+ as acceptor
1.8.1.1 created 1961, deleted 1972
