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EC 4.1.1.86 Details
EC number
4.1.1.86
Accepted name
diaminobutyrate decarboxylase
Reaction
L-2,4-diaminobutanoate = propane-1,3-diamine + CO2
Other name(s)
DABA DC, L-2,4-diaminobutyrate decarboxylase, L-2,4-diaminobutanoate carboxy-lyase
Systematic name
L-2,4-diaminobutanoate carboxy-lyase (propane-1,3-diamine-forming)
Comment
A pyridoxal-phosphate protein that requires a divalent cation for activity [1]. N4-Acetyl-L-2,4-diaminobutanoate, 2,3-diaminopropanoate, ornithine and lysine are not substrates. Found in the proteobacteria Haemophilus influenzae and Acinetobacter baumannii. In the latter, this enzyme is cotranscribed with the dat gene that encodes EC 2.6.1.76, diaminobutyrate—2-oxoglutarate transaminase, which can supply the substrate for this enzyme.
History
created 2006
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