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EC 1.8.2.2 Details
EC number
1.8.2.2
Accepted name
thiosulfate dehydrogenase
Reaction
2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c
Other name(s)
tsdA (gene name), tetrathionate synthase, thiosulfate oxidase, thiosulfate-oxidizing enzyme, thiosulfate-acceptor oxidoreductase
Systematic name
thiosulfate:ferricytochrome-c oxidoreductase
CAS registry number
9076-88-4
Comment
The enzyme catalyses the reversible formation of a sulfur-sulfur bond between the sulfane atoms of two thiosulfate molecules, yielding tetrathionate and releasing two electrons. In many bacterial species the enzyme is a diheme c-type cytochrome. In a number of organisms, including Thiomonas intermedia and Sideroxydans lithotrophicus, a second diheme cytochrome (TsdB) acts as the electron acceptor. However, some organisms, such as Allochromatium vinosum, lack TsdB. The electron acceptor in these organisms may be the high-potential iron-sulfur protein (HiPIP).
History
created 1990
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