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EC 1.14.11.44 Details
show Brenda entryEC number
1.14.11.44
Accepted name
(R)-dichlorprop dioxygenase (2-oxoglutarate)
Reaction
(1) (R)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2 = 4-chloro-2-methylphenol + pyruvate + succinate + CO2;;
(2) (R)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 = 2,4-dichlorophenol + pyruvate + succinate + CO2
Other name(s)
RdpA,
α-ketoglutarate-dependent (R)-dichlorprop dioxygenase,
(R)-phenoxypropionate/α-ketoglutarate-dioxygenase,
2-oxoglutarate-dependent (R)-dichlorprop dioxygenase,
(R)-mecoprop dioxygenase,
2-oxoglutarate-dependent (R)-mecoprop dioxygenase
Systematic name
(R)-2-(4-chloro-2-methylphenoxy)propanoate,2-oxoglutarate:oxygen oxidoreductase (pyruvate-forming)
Comment
Fe2+-dependent enzyme. The enzymes from the Gram-negative bacteria Delftia acidovorans MC1 and Sphingomonas herbicidovorans MH are involved in the degradation of the (R)-enantiomer of the phenoxyalkanoic acid herbicides mecoprop and dichlorprop [1,2].
History
created 2013
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1 Oxidoreductases
3 Hydrolases
3.6.3.13 created 2000, deleted 2001
