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EC 3.6.3.49 Details
EC number
3.6.3.49
Accepted name
channel-conductance-controlling ATPase
Reaction
ATP + H2O = ADP + phosphate
Systematic name
ATP phosphohydrolase (channel-conductance-controlling)
Comment
ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. An animal enzyme that is active in forming a chloride channel, the absence of which brings about cystic fibrosis. It is also involved in the functioning of other transmembrane channels.
History
created 2000, deleted 2018
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