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EC 3.1.1.2 Details
EC number
3.1.1.2
Accepted name
arylesterase
Reaction
a phenyl acetate + H2O = a phenol + acetate
Other name(s)
A-esterase (ambiguous), paraoxonase (ambiguous), aromatic esterase
Systematic name
aryl-ester hydrolase
CAS registry number
9032-73-9
Comment
Acts on many phenolic esters. The reactions of EC 3.1.8.1 aryldialkylphosphatase, were previously attributed to this enzyme. It is likely that the three forms of human paraoxonase are lactonases rather than aromatic esterases [7,8]. The natural substrates of the paraoxonases are lactones [7,8], with (±)-5-hydroxy-6E,8Z,11Z,4Z-eicostetraenoic-acid 1,5-lactone being the best substrate [8].
History
created 1961, modified 1989
EC Tree
3.1.1.9 created 1961, deleted 1972
3.1.1.12 created 1961, deleted 1972
3.1.1.16 created 1961, deleted 1972
3.1.1.18 created 1961, deleted 1982
3.1.1.62 created 1989, deleted 1992
3.1.1.69 created 1992, deleted 2002