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EC 2.8.3.17 Details
EC number
2.8.3.17
Accepted name
3-(aryl)acryloyl-CoA:(R)-3-(aryl)lactate CoA-transferase
Reaction
(1) (E)-cinnamoyl-CoA + (R)-(phenyl)lactate = (E)-cinnamate + (R)-(phenyl)lactoyl-CoA;;(2) (E)-4-coumaroyl-CoA + (R)-3-(4-hydroxyphenyl)lactate = 4-coumarate + (R)-3-(4-hydroxyphenyl)lactoyl-CoA;;(3) 3-(indol-3-yl)acryloyl-CoA + (R)-3-(indol-3-yl)lactate = 3-(indol-3-yl)acrylate + (R)-3-(indol-3-yl)lactoyl-CoA
Other name(s)
FldA, cinnamoyl-CoA:phenyllactate CoA-transferase
Systematic name
3-(aryl)acryloyl-CoA:(R)-3-(aryl)lactate CoA-transferase
CAS registry number
289682-21-9
Comment
The enzyme, found in some amino acid-fermenting anaerobic bacteria, participates in the fermentation pathways of L-phenylalanine, L-tyrosine, and L-tryptophan. It forms a complex with EC 4.2.1.175, (R)-3-(aryl)lactoyl-CoA dehydratase.
History
created 2003, modified 2019
EC Tree
3.1.1.9 created 1961, deleted 1972
3.1.1.12 created 1961, deleted 1972
3.1.1.16 created 1961, deleted 1972
3.1.1.18 created 1961, deleted 1982
3.1.1.62 created 1989, deleted 1992
3.1.1.69 created 1992, deleted 2002