Any feedback?
Please rate this page
(ecexplorer.php)
(0/150)

BRENDA support

EC Explorer

EC 3.1.4.14 Details
EC number
3.1.4.14
Accepted name
[acyl-carrier-protein] phosphodiesterase
Reaction
holo-[acyl-carrier protein] + H2O = 4′-phosphopantetheine + apo-[acyl-carrier protein]
Other name(s)
ACP hydrolyase, ACP phosphodiesterase, AcpH, [acyl-carrier-protein] 4′-pantetheine-phosphohydrolase, holo-[acyl-carrier-protein] 4′-pantetheine-phosphohydrolase
Systematic name
holo-[acyl-carrier protein] 4′-pantetheine-phosphohydrolase
CAS registry number
37288-21-4
Comment
The enzyme cleaves acyl-[acyl-carrier-protein] species with acyl chains of 6-16 carbon atoms although it appears to demonstrate a preference for the unacylated acyl-carrier protein (ACP) and short-chain ACPs over the medium- and long-chain species [3]. Deletion of the gene encoding this enzyme abolishes ACP prosthetic-group turnover in vivo [3]. Activation of apo-ACP to form the holoenzyme is carried out by EC 2.7.8.7, holo-[acyl-carrier-protein] synthase.
History
created 1972, modified 2006
EC Tree
3.1.1.9 created 1961, deleted 1972
3.1.1.12 created 1961, deleted 1972
3.1.1.16 created 1961, deleted 1972
3.1.1.18 created 1961, deleted 1982
3.1.1.62 created 1989, deleted 1992
3.1.1.69 created 1992, deleted 2002
3.1.4.5 created 1961, deleted 1978
3.1.4.6 created 1961, deleted 1978
3.1.4.7 created 1961, deleted 1978
3.1.4.8 created 1961, transferred 1965 to EC 2.7.7.26, reinstated 1972, deleted 1978
3.1.4.9 created 1965, deleted 1978
3.1.4.10 created 1972, modified 1976, deleted 2002
3.1.4.18 created 1972, deleted 1978
3.1.4.19 created 1972, deleted 1978
3.1.4.20 created 1972, deleted 1978
3.1.4.21 created 1972, deleted 1978
3.1.4.22 created 1972, deleted 1978
3.1.4.23 created 1972, deleted 1978
3.1.4.24 created 1972, deleted 1978
3.1.4.25 created 1972, deleted 1978
3.1.4.26 created 1972, deleted 1978
3.1.4.27 created 1972, deleted 1978
3.1.4.28 created 1972, deleted 1978
3.1.4.29 created 1972, deleted 1978
3.1.4.30 created 1972, deleted 1978
3.1.4.31 created 1972, deleted 1978
3.1.4.32 created 1972, deleted 1978
3.1.4.33 created 1972, deleted 1978
3.1.4.34 created 1972, deleted 1978
3.1.4.36 created 1976, deleted 2002
3.1.4.47 created 1989, deleted 2002