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EC 1.1.99.7 Details
EC number
1.1.99.7
Accepted name
lactate—malate transhydrogenase
Reaction
(S)-lactate + oxaloacetate = pyruvate + malate
Other name(s)
malate-lactate transhydrogenase
Systematic name
(S)-lactate:oxaloacetate oxidoreductase
CAS registry number
9077-15-0
Comment
Catalyses hydrogen transfer from C3 or C4 (S)-2-hydroxy acids to 2-oxo acids. It contains tightly bound nicotinamide nucleotide in its active centre. This prosthetic group cannot be removed without denaturation of the protein.
History
created 1972