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EC 1.1.3.15 Details
EC number
1.1.3.15
Accepted name
(S)-2-hydroxy-acid oxidase
Reaction
an (S)-2-hydroxy carboxylate + O2 = a 2-oxo carboxylate + H2O2
Other name(s)
hydroxy-acid oxidase A, hydroxy-acid oxidase B, glycolate oxidase, L-2-hydroxy acid oxidase, hydroxyacid oxidase A, L-α-hydroxy acid oxidase
Systematic name
(S)-2-hydroxy carboxylate:oxygen 2-oxidoreductase
CAS registry number
9028-71-1
Comment
A flavoprotein (FMN). Exists as two major isoenzymes; the A form preferentially oxidizes short-chain aliphatic hydroxy acids, and was previously listed as EC 1.1.3.1, glycolate oxidase; the B form preferentially oxidizes long-chain and aromatic hydroxy acids. The rat isoenzyme B also acts as EC 1.4.3.2, L-amino-acid oxidase.
History
created 1972 (EC 1.1.3.1 created 1961, incorporated 1984)