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EC 1.1.1.287 Details
EC number
1.1.1.287
Accepted name
D-arabinitol dehydrogenase (NADP+)
Reaction
(1) D-arabinitol + NADP+ = D-xylulose + NADPH + H+;;(2) D-arabinitol + NADP+ = D-ribulose + NADPH + H+
Other name(s)
NADP+-dependent D-arabitol dehydrogenase, ARD1p, D-arabitol dehydrogenase 1
Systematic name
D-arabinitol:NADP+ oxidoreductase
Comment
The enzyme from the rust fungus Uromyces fabae can use D-arabinitol and D-mannitol as substrates in the forward direction and D-xylulose, D-ribulose and, to a lesser extent, D-fructose as substrates in the reverse direction. This enzyme carries out the reactions of both EC 1.1.1.11, D-arabinitol 4-dehydrogenase and EC 1.1.1.250, D-arabinitol 2-dehydrogenase, but unlike them, uses NADP+ rather than NAD+ as cofactor. D-Arabinitol is capable of quenching reactive oxygen species involved in defense reactions of the host plant.
History
created 2005