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EC 1.1.1.282 Details
show Brenda entryEC number
1.1.1.282
Accepted name
quinate/shikimate dehydrogenase [NAD(P)+]
Reaction
(1) L-quinate + NAD(P)+ = 3-dehydroquinate + NAD(P)H + H+;;(2) shikimate + NAD(P)+ = 3-dehydroshikimate + NAD(P)H + H+
Other name(s)
YdiB,
quinate/shikimate dehydrogenase (ambiguous)
Systematic name
L-quinate:NAD(P)+ 3-oxidoreductase
Comment
This is the second shikimate dehydrogenase enzyme found in Escherichia coli. It can use both quinate and shikimate as substrates and either NAD+ or NADP+ as acceptor. The low catalytic efficiency with both quinate and shikimate suggests that neither may be the physiological substrate. cf. EC 1.1.1.24, quinate/shikimate dehydrogenase (NAD+), EC 1.1.5.8, quinate/shikimate dehydrogenase (quinone), and EC 1.1.1.25, shikimate dehydrogenase (NADP+).
History
created 2004, modified 2021
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1 Oxidoreductases
