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EC 1.1.1.281 Details
show Brenda entryEC number
1.1.1.281
Accepted name
GDP-4-dehydro-6-deoxy-D-mannose reductase
Reaction
GDP-α-D-rhamnose + NAD(P)+ = GDP-4-dehydro-α-D-rhamnose + NAD(P)H + H+
Other name(s)
GDP-4-keto-6-deoxy-D-mannose reductase [ambiguous],
GDP-6-deoxy-D-lyxo-4-hexulose reductase,
Rmd,
GDP-6-deoxy-D-mannose:NAD(P)+ 4-oxidoreductase (D-rhamnose-forming),
GDP-6-deoxy-α-D-mannose:NAD(P)+ 4-oxidoreductase (D-rhamnose-forming)
Systematic name
GDP-α-D-rhamnose:NAD(P)+ 4-oxidoreductase
Comment
This enzyme differs from EC 1.1.1.187, GDP-4-dehydro-D-rhamnose reductase, in that the only product formed is GDP-α-D-rhamnose. D-Rhamnose is a constituent of lipopolysaccharides of Gram-negative plant and human pathogenic bacteria.
History
created 2004
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1 Oxidoreductases
