7.6.2.9: ABC-type quaternary amine transporter
This is an abbreviated version!
For detailed information about ABC-type quaternary amine transporter, go to the full flat file.
Word Map on EC 7.6.2.9
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7.6.2.9
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cassette
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multidrug
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p-glycoprotein
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nucleotide-binding
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toxin
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streptococcus
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lipoprotein
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xenobiotics
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bacteriocins
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azole
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doxorubicin
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verapamil
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siderophore
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cftr
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resistance-associated
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chemoresistance
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lactococcus
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two-component
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hoechst
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cystic
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rhodamine
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elasticum
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atp-bound
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nisin
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mitoxantrone
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molecular biology
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cry1ac
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abc-transporter
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abcb11
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azole-resistant
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calcein
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ivermectin
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proteoliposomes
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atp-driven
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lantibiotic
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abcg2-mediated
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pseudoxanthoma
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flippase
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abccs
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transporter-mediated
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thuringiensis
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triphosphate-binding
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outward-facing
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canalicular
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stargardt
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bacitracin
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adrenoleukodystrophy
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fluconazole
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nucleotide-free
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itraconazole
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inward-facing
- 7.6.2.9
- cassette
-
multidrug
- p-glycoprotein
-
nucleotide-binding
- toxin
- streptococcus
- lipoprotein
- xenobiotics
-
bacteriocins
- azole
- doxorubicin
- verapamil
-
siderophore
- cftr
-
resistance-associated
-
chemoresistance
- lactococcus
-
two-component
-
hoechst
-
cystic
- rhodamine
- elasticum
-
atp-bound
- nisin
- mitoxantrone
- molecular biology
-
cry1ac
-
abc-transporter
-
abcb11
-
azole-resistant
-
calcein
- ivermectin
-
proteoliposomes
-
atp-driven
-
lantibiotic
-
abcg2-mediated
-
pseudoxanthoma
- flippase
-
abccs
-
transporter-mediated
- thuringiensis
-
triphosphate-binding
-
outward-facing
-
canalicular
- stargardt
- bacitracin
- adrenoleukodystrophy
- fluconazole
-
nucleotide-free
- itraconazole
-
inward-facing
Reaction
Synonyms
ABC transporter, BetTA.halophytica, EC 3.6.3.32, glycine betaine porter II, glycine betaine transport system permease protein, glycine betaine transporter membrane protein, glycine betaine-binding protein, glycine betaine-binding protein OpuAC, glycine betaine/carnitine/choline-binding protein, glycine/betaine ABC transporter, N288_21505, N288_21525, N288_25665, OpuA, OpuAB, OpuAC, OpuB, OpuBC, OpuC, OpuCC, OpuD, OpuF, OpuF transporter, proline/betaine ABC transporter permease, ProU, proW, Quaternary-amine-transporting ATPase
ECTree
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Metals Ions
Metals Ions on EC 7.6.2.9 - ABC-type quaternary amine transporter
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Ba2+
bivalent cations more effective activators than monovalent cations
K+
K3PO4
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100 mosmol/kg osmolality, pH 7.0, stimulates OpuA activity. 200 mM, stimulates ATPase activity
Mg2+
Na+
NH4+
less effective than KCl, in the presence of the protonophore SF6847 much more effective
Sodium phosphate
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100 mosmol/kg osmolality, pH 7.0, stimulates OpuA activity
additional information
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K+ binding site within the nucleotide-binding protein domain, stimulation of the nucleotide-binding protein domain 4fold higher than with Na+
K+
maximal enzyme activity reached with 250 mM KCl, no further effect in the presence of the protonophore SF6847
Mg2+
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significant reduction of glycine betaine efflux when 6 mM ADP/Mg2+ is added to the reaction
Mg2+
bivalent cations more effective activators than monovalent cations
Mg2+
A0A077T980; A0A077T7U5; A0A077T7Z1, A0A097A5F2; A0A077T7R8
required
Na+
-
stimulation of the nucleotide-binding protein domain 4fold lower than with K+
Na+
-
osmotically activated but does not require high concentrations for activity
K+, Li+, Cs+, Rb+, NH4+, Ca2+, and Mg2+ show no effect