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7.6.2.1: P-type phospholipid transporter

This is an abbreviated version!
For detailed information about P-type phospholipid transporter, go to the full flat file.

Word Map on EC 7.6.2.1

Reaction

ATP
+
H2O
+
phospholipid [side 1]
=
ADP
+
phosphate
+
phospholipid [side 2]

Synonyms

ABCB1, ABCB4, ALA1, ALA10, ALA11, ALA12, ALA2, ALA3, ALA4, ALA5, ALA7, ALA8, ALA9, aminophospholipid ATPase, aminophospholipid flippase, aminophospholipid flippase 10, aminophospholipid flippase 11, aminophospholipid flippase 12, aminophospholipid scramblase, aminophospholipid translocase, aminophospholipid translocase VC, aminophospholipid transporter, aminophospholipid-translocase, aminophosphoplipid translocase, APLT, ATP phosphohydrolase (phospholipid-flipping), ATP-dependent specific phospholipid flippase, ATP-independent flippase, ATP-independent long-chain phosphatidylcholine translocator, ATP10A, ATP10B, ATP10D, ATP11A, ATP11B, ATP11C, ATP8A1, Atp8a2, ATP8B1, ATP8B2, ATP8B3, ATP8B4, ATP8B5, ATP9A, ATP9B, ATPase II, ATPVC, ATPVD, CDC50A, Cdc50p-Drs2p, Cfs1p, Dnf1, Dnf1 |, Dnf1p, Dnf1p and Dnf2p, Dnf1p-Lem3p, Dnf2, Dnf2p, Dnf3, Dnf3p, Drs2, Drs2-dependent phosphatidylserine translocase, Drs2p, EC 3.6.3.1, EC 3.6.3.13, energy-dependent lipid flippase, energy-independent lipid flippase, EpsE, erythroid ATP-dependent aminophospholipid transporter, flippase, glycerophospholipid flippase, HUSSY-20, inward-directed phospholipid translocase, LdMT, LdRos3, lipid flippase, LMT translocase, M5-DLO flippase, Man5GlcNAc2-PP-dolichol flippase, MDR3 P-glycoprotein, Mg2+-ATPase, Mg2+-ATPase A, miltefosine transporter, More, MsbA, multidrug resistance 3 P-glycoprotein, MurJ, MviN, Neo1, Neo1p, P type aminophospholipid transporter, P-glycoprotein, P-gp, P4 ATPase ALA1, P4-ATPase, P4-type ATPase, PC-flippase, peptidoglycan lipid II flippase, phosphatidylserine flippase, phosphatidylserine translocase, phosphatidylserine translocase/ATPase, phospholipid flippase, phospholipid scramblase, phospholipid scramblase 1, phospholipid scramblase 3, phospholipid scrambling activity, phospholipid translocase, phospholipid-translocase, phospholipid-translocating ATPase, phospholipid-transporting ATPase IB, PL flippase, PL scramblase, PLS3, PLSCR1, PLSCR2, PLSCR3, PLSCR4, PS flippase, PS translocase, PS-flippase, scramblase, SCRM-1, sphingomyelin flippase, TAT-1, TAT-2, TAT-3, TAT-4, TAT-5, TAT-6, transbilayer amphipath transporter, transbilayer amphipath transporter-1, type 4 P-type ATPas, type II secretion ATPase, type IV P-type ATPase

ECTree

     7 Translocases
         7.6 Catalysing the translocation of other compounds
             7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
                7.6.2.1 P-type phospholipid transporter

Source Tissue

Source Tissue on EC 7.6.2.1 - P-type phospholipid transporter

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
-
epithelial cells
Manually annotated by BRENDA team
-
adult ventricular
Manually annotated by BRENDA team
-
neonatal rat cardiomyoblasts
Manually annotated by BRENDA team
-
promyelocytic leukemia cells
Manually annotated by BRENDA team
TAT-1 is differentially spliced during development, isozyme TAT-1C-specific splicing occurs in the intestine
Manually annotated by BRENDA team
high distribution in pancreas
Manually annotated by BRENDA team
-
expression analysis of isozymes Atp8a1 and flippase in reticulocytes, overview
Manually annotated by BRENDA team
high distribution in small intestine
Manually annotated by BRENDA team
ATP8B3 is expressed only in germ cells, especially in haploid spermatids
Manually annotated by BRENDA team
additional information