7.5.2.1: ABC-type maltose transporter
This is an abbreviated version!
For detailed information about ABC-type maltose transporter, go to the full flat file.
Word Map on EC 7.5.2.1
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7.5.2.1
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maltose-binding
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maltodextrins
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outward-facing
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proteoliposomes
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maltotriose
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nanodiscs
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atp-bound
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inward-facing
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atp-binding-cassette
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lager
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q-loops
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eiiaglc
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analysis
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synthesis
- 7.5.2.1
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maltose-binding
- maltodextrins
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outward-facing
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proteoliposomes
- maltotriose
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nanodiscs
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atp-bound
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inward-facing
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atp-binding-cassette
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lager
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q-loops
- eiiaglc
- analysis
- synthesis
Reaction
Synonyms
ATP phosphohydrolase (maltose-importing), Cg2463, EC 3.6.3.19, GlvC, Mal-EFGK2, Mal11, MalE, MalE-FGK2, MalF, MalFGK2, MalFGK2-E, MalG511, MalK, MalK2, malK3, MalP, MalT, MALT2, MALT4, maltose ABC transporter, maltose ABC transporter MALFGK2-E, maltose ABC-type transporter, maltose ATP binding cassette transporter, maltose ATP-binding cassette importer, maltose ATP-binding cassette transporter, maltose importer, maltose transporter, maltose transporter ATPase, maltose transporter MalFGK2, maltose-specific enzyme IICB, maltose-transporting ATPase, maltose/maltodextrin ABC transporter, More, MuSK, proton-maltose symporter
ECTree
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Natural Substrates Products
Natural Substrates Products on EC 7.5.2.1 - ABC-type maltose transporter
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REACTION DIAGRAM
ATP + H2O + maltose-[maltose-binding protein][side 1]
ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]
ATP + H2O + maltose-[maltose-binding protein][side 1] + H+[side1]
ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1] + H+[side2]
ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]
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ATP + H2O + maltose-[maltose-binding protein][side 1]
ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]
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ATP + H2O + maltose-[maltose-binding protein][side 1]
ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]
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ATP + H2O + maltose-[maltose-binding protein][side 1]
ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]
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ATP + H2O + maltose-[maltose-binding protein][side 1]
ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]
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ATP + H2O + maltose-[maltose-binding protein][side 1]
ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]
P68187; P68183; P02916
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ATP + H2O + maltose-[maltose-binding protein][side 1]
ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]
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ATP + H2O + maltose-[maltose-binding protein][side 1]
ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]
Saccharomyces eubayanus CBS 12357T
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ATP + H2O + maltose-[maltose-binding protein][side 1]
ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1]
Q9X0S9; Q9X2F5
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ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1] + H+[side2]
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ATP + H2O + maltose-[maltose-binding protein][side 1] + H+[side1]
ADP + phosphate + maltose[side 2] + [maltose-binding protein][side 1] + H+[side2]
Saccharomyces cerevisiae IMK289
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ADP + phosphate + maltose/in
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ATP + H2O + maltose/out
ADP + phosphate + maltose/in
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ATP + H2O + maltose/out
ADP + phosphate + maltose/in
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ATP + H2O + maltose/out
ADP + phosphate + maltose/in
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ATP + H2O + maltose/out
ADP + phosphate + maltose/in
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the peripheral membrane protein MalK associates with integral cytoplasmic membrane proteins MalF and MalG to form the maltose transport complex MalFGK. In addition malK participates in two different regulatory pathways which modulate mal gene expression and MalFGK transport activity
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ATP + H2O + maltose/out
ADP + phosphate + maltose/in
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extracytoplasmic anchoring of the substrate binding protein, the receptor, is emerging as key determinant for the structural rearrangements in the cytoplasmically exposed ATP-binding cassette domains and in the transmembrane gates during the nucleotide cycle, molecular mechanism, overview
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ATP + H2O + maltose/out
ADP + phosphate + maltose/in
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ATP + H2O + maltose/out
ADP + phosphate + maltose/in
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translocation of maltose across biological membranes
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interactions of MalK with the regulatory proteins MalT and enzyme IIAglc
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additional information
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concomitantly with the three conformations of the ATP-binding cassette MalK2, three functionally relevant conformations are found also in the periplasmic MalF-P2 loop, strictly dependent on cytoplasmic nucleotide-binding and periplasmic docking of liganded MalE to MalFG, overview
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additional information
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MalK is the ABC-ATPase of the maltose importer of Escherichia coli. The MalK accessory domain interacts with at least two enzymes, MalT and IIA
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additional information
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MalK is the ABC-ATPase of the maltose importer of Escherichia coli. The MalK accessory domain interacts with at least two enzymes, MalT and IIA
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additional information
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the MalF P2 loop plays an important role in intersubunit communication. In particular, this loop is involved in keeping MalE in close contact with the transporter. the MalF P2 loop of the ATP-binding cassette transporter MalFGK2 interacts with maltose binding protein MalE throughout the catalytic cycle, overview
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additional information
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stabilization of the semi-open MalK2 conformation by maltose-bound maltose-binding protein is key to the coupling of maltose transport to ATP hydrolysis in vivo, because it facilitates the progression of the MalK dimer from the open to the semi-open conformation, from which it can proceed to hydrolyze ATP
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additional information
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stabilization of the semi-open MalK2 conformation by maltose-bound maltose-binding protein is key to the coupling of maltose transport to ATP hydrolysis in vivo, because it facilitates the progression of the MalK dimer from the open to the semi-open conformation, from which it can proceed to hydrolyze ATP
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additional information
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the MalF P2 loop plays an important role in intersubunit communication. In particular, this loop is involved in keeping MalE in close contact with the transporter. the MalF P2 loop of the ATP-binding cassette transporter MalFGK2 interacts with maltose binding protein MalE throughout the catalytic cycle, overview
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