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7.5.2.1: ABC-type maltose transporter

This is an abbreviated version!
For detailed information about ABC-type maltose transporter, go to the full flat file.

Word Map on EC 7.5.2.1

Reaction

ATP
+
H2O
+
maltose-[maltose-binding protein][side 1]
=
ADP
+
phosphate
+
maltose[side 2]
+
[maltose-binding protein][side 1]

Synonyms

ATP phosphohydrolase (maltose-importing), Cg2463, EC 3.6.3.19, GlvC, Mal-EFGK2, Mal11, MalE, MalE-FGK2, MalF, MalFGK2, MalFGK2-E, MalG511, MalK, MalK2, malK3, MalP, MalT, MALT2, MALT4, maltose ABC transporter, maltose ABC transporter MALFGK2-E, maltose ABC-type transporter, maltose ATP binding cassette transporter, maltose ATP-binding cassette importer, maltose ATP-binding cassette transporter, maltose importer, maltose transporter, maltose transporter ATPase, maltose transporter MalFGK2, maltose-specific enzyme IICB, maltose-transporting ATPase, maltose/maltodextrin ABC transporter, More, MuSK, proton-maltose symporter

ECTree

     7 Translocases
         7.5 Catalysing the translocation of carbohydrates and their derivatives
             7.5.2 Linked to the hydrolysis of a nucleoside triphosphate
                7.5.2.1 ABC-type maltose transporter

Inhibitors

Inhibitors on EC 7.5.2.1 - ABC-type maltose transporter

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Aes
-
antagonizing maltotriose binding by MalT
-
alpha-cyclodextrin
-
-
antibody 4H12
-
recognizes the peptide 111-NQRVNQVAEVLQL-123
-
antibody 5B5
-
recognizes the peptide 53-ETITSGDLTRM-67
-
beta-cyclodextrin
-
-
EIIAGlc
-
when glucose as preferred carbon source is transported, EIIAGlc becomes predominantly unphosphorylated and allosterically inhibits several permeases, including MalFGK2, which possesses a specific binding site in region III of EIIAGlc, in a process termed inducer exclusion involving the N-terminal part of the inhibitor, binding surface, overview
-
enzyme IIA(Glc)
-
inhibits the maltose ATP-binding cassette transporter MalE-FGK2 by interaction with the nucleotide-binding and -hydrolyzing subunit MalK
-
enzyme IIAglc
-
-
-
gamma-cyclodextrin
-
-
MalK
-
0.008 mM, in the absence of maltotriose 80% inhibition, no inhibition in the presence of 0.1 mM maltotriose
-
maltose binding protein
-
inhibitory above 0.05 mM
-
MalY
-
antagonizing maltotriose binding by MalT
-
NaN3
-
FGK2 complex
p-chloromercuriphenyl sulfonic acid
-
FGK2 complex
vanadate