7.2.2.3: P-type Na+ transporter

This is an abbreviated version!
For detailed information about P-type Na+ transporter, go to the full flat file.

Word Map on EC 7.2.2.3

7.2.2.3

cardiac

erythrocyte

ouabain-sensitive

atpases

hypertension

myosin

sarcoplasmic

electrogenic

contractile

ca2+-atpase

nerve

arterial

gill

basolateral

glycoside

sodium-potassium

tubule

na,k-atpase

depolarization

migraine

alpha-subunits

digoxin

hyperpolarization

cotransporter

myofibrillar

vanadate

normotensive

inotropic

h+-atpase

cytochemical

cardiotonic

amiloride

sarcolemmal

mg2+-dependent

transepithelial

digitalis

aura

k+-dependent

phosphoenzyme

oligomycin

rb+

actomyosin

branchial

osmoregulatory

dicyclohexylcarbodiimide

natriuresis

hemiplegia

menkes

proton-translocating

serca

medicine

biotechnology

pharmacology

Reaction

+ n Na+[side 1] =

+ n Na+[side 2]

Synonyms

adenosine 5'-triphosphatase, adenosine triphosphatase, ATP hydrolase, ATP1A2, ATP4, ATPase, complex V (mitochondrial electron transport), EC 3.6.3.7, EC 3.6.3.9, ENA, Ena1, Ena1p, KPA1, KPA2, Na+ stimulated P-type ATPase, Na+,K+-ATPase, Na+-ATPase, Na+-exporting ATPase, Na+-K+-ATPase alpha-2 subunit, Na+-stimulated ATPase, Na+/K+-ATPase, Na+/K+-ATPase sodium pump, NtpK, ouabain-insensitive Na+-ATPase, P-type ATPase, P-Type Na+ ATPase, P-type Na+-ATPase, P2-type ATPase, renal Na+-ATPase, sodium ATPase, sodium pump, sodium pump alpha1 subunit, sodium pump Ena1p, sodium-pump ATPase, TcENA, vacuolar-type ATPase

ECTree

7 Translocases

7.2 Catalysing the translocation of inorganic cations

7.2.2 Linked to the hydrolysis of a nucleoside triphosphate

7.2.2.3 P-type Na+ transporter

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Results	in table
26	Activating Compound
41	AA Sequence
21	Application
1	CAS Registry Number
24	Cloned(Commentary)
4467	Disease/ Diagnostics
13	Expression
14	General Information
14	IC50 Value
131	Inhibitors
20	KM Value [mM]
37	Localization
44	Metals/Ions
52	Molecular Weight [Da]
30	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
165	Organism
16	pH Optimum
2	pH Range
1	pH Stability
1	pI Value
11	Posttranslational Modification
16	Protein Variants
19	Purification (Commentary)
10	Reaction
12	Reaction Type
89	Reference
40	Source Tissue
25	Specific Activity [micromol/min/mg]
3	Storage Stability
78	Substrates and Products (Substrate)
15	Subunits
87	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
1	Temperature Stability [°C]

IC50 Value

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IC50 Value on EC 7.2.2.3 - P-type Na+ transporter

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0.00001

(3beta,22alpha,25R)-26-(beta-D-glucopyranosyloxy)-2-methoxyfurost-5-en-3-yl O-D-apio-beta-D-furanosyl-(1-2)-O-[6-deoxy-alpha-L-mannopyranosyl-(1-4)]-beta-D-glucopyranoside

Sus scrofa

obtained by extrapolation of half maximal inhibition

701427

0.000001

(3beta,22alpha,25R)-spirostan-3-yl O-D-apio-beta-D-furanosyl-(1-2)-O-[6-deoxy-alpha-L-mannopyranosyl-(1-4)]-beta-D-glucopyranoside

Sus scrofa

obtained by extrapolation of half maximal inhibition

701427

0.0001

ceramide

Sus scrofa

pH 7.4, 37°C

711013

12.3 - 32.5

cipargamin

3 entries

0.22 - 0.5

Furosemide

3 entries

0.044

miltefosine

Trypanosoma cruzi

695869

0.0001

sodium orthovanadate

Leishmania amazonensis

686609

0.0091

vanadate

Cavia porcellus

B3SI05

pH and temperature not specified in the publication

718973

0.053 - 0.095

[(dihydroindenyl)oxy]acetic acid

2 entries