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7.2.2.3: P-type Na+ transporter

This is an abbreviated version!
For detailed information about P-type Na+ transporter, go to the full flat file.

Word Map on EC 7.2.2.3

Reaction

ATP
+
H2O
 + n Na+[side 1] =
ADP
 +
phosphate
 + n Na+[side 2]

Synonyms

adenosine 5'-triphosphatase, adenosine triphosphatase, ATP hydrolase, ATP1A2, ATP4, ATPase, complex V (mitochondrial electron transport), EC 3.6.3.7, EC 3.6.3.9, ENA, Ena1, Ena1p, KPA1, KPA2, Na+ stimulated P-type ATPase, Na+,K+-ATPase, Na+-ATPase, Na+-exporting ATPase, Na+-K+-ATPase alpha-2 subunit, Na+-stimulated ATPase, Na+/K+-ATPase, Na+/K+-ATPase sodium pump, NtpK, ouabain-insensitive Na+-ATPase, P-type ATPase, P-Type Na+ ATPase, P-type Na+-ATPase, P2-type ATPase, renal Na+-ATPase, sodium ATPase, sodium pump, sodium pump alpha1 subunit, sodium pump Ena1p, sodium-pump ATPase, TcENA, vacuolar-type ATPase

ECTree

     7 Translocases
         7.2 Catalysing the translocation of inorganic cations
             7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
                7.2.2.3 P-type Na+ transporter

Cloned

Cloned on EC 7.2.2.3 - P-type Na+ transporter

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
+AHw-PCR products for the cytoplasmic-loop regions of the ATPase cloned into plasmid vectors and sequenced+AHwAfA-
expressed in Saccharomyces cerevisiae strain w303-1a
expression in Saccharomyces cerevisiae
expression in Saccharomyces cerevisiae ena1-4 nha1 mutant, sensitive to high K+ and Na+ concentrations
expression in Sacharomyces cerevisiae
into tht pCR II-TOPO vector, into the mammalian expression vector pEGFP-N1 for transfection of FreeStyle 293-F cells, and into the trypanosomatid shuttle vector pTREX for transformation of Trypanosoma cruzi epimastigotes
PCR products for the cytoplasmic-loop regions of the ATPase cloned into plasmid vectors and sequenced