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7.2.2.13: Na+/K+-exchanging ATPase

This is an abbreviated version!
For detailed information about Na+/K+-exchanging ATPase, go to the full flat file.

Word Map on EC 7.2.2.13

Reaction

ATP
+
H2O
 +
Na+[side 1]
 +
K+[side 2]
=
ADP
 +
phosphate
 +
Na+[side 2]
 +
K+[side 1]

Synonyms

(Na+ + K+)-activated ATPase, (Na+ + K+)-ATPase, (Na+, K+)-ATPase, (Na+, K+)-dependent ATPase, (Na+,K+)-activated ATPase, (Na+-K+)-ATPase, alpha2Na+/K+-ATPase, ATP1a1, atp1a1a, ATPalpha, EC 3.6.1.3, EC 3.6.1.37, EC 3.6.3.9, Na pump, Na(+)-K(+)-exchanging ATPase, Na+ pump, Na+, K+ -ATPase, Na+, K+-ATPase, Na+,K+ pump, Na+,K+-adenosine triphosphatase, Na+,K+-ATPase, Na+,K+-pump, Na+-K+ ATPase, Na+-K+ pump, Na+-K+ pump alpha1-isoform, Na+-K+ pump alpha2-isoform, Na+-K+-ATPase, Na+-K+-ATPase alpha2-isoform, Na+-K+-pump, Na+/K+ -ATPase, Na+/K+ ATPase, Na+/K+ pump, Na+/K+-ATPase, Na+K+-ATPase, Na+K+ATPase, Na, K-ATPase, Na,K pump, Na,K-activated ATPase, Na,K-adenosine triphosphatase, Na,K-ATPase, Na,K-Pump, Na-K-ATPase, Na/K pump, Na/K-ATPase, NKA, Nkaalpha protein, nkaalpha1, nkaalpha3a, nkaalpha3b, renal sodium-potassium pump, SNaK1, sodium potassium adenosinetriphosphatase, sodium pump, sodium-potassium pump, sodium/potassium ATPase

ECTree

     7 Translocases
         7.2 Catalysing the translocation of inorganic cations
             7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
                7.2.2.13 Na+/K+-exchanging ATPase

Molecular Weight

Molecular Weight on EC 7.2.2.13 - Na+/K+-exchanging ATPase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100000
108000
-
x * 108000, alpha subunit, SDS-PAGE
110000
111817
-
x * 111817, calculated from nucleotide sequence
112000
113000
x * 113000, alpha subunit, calculated from amino acid sequence
115000
-
x * 115000, alpha3 isoform, SDS-PAGE
155000
-
non-denaturing PAGE
250000 - 300000
-
radiation inactivation , gel filtration
35000
379000
shark
-
equilibrium sedimentation
38000
-
x * 100000, alpha-subunit, + x * 38000, beta-subunit, the ratio of alpha: beta is 1:1
380000
-
equilibrium centrifugation
45000
-
1 * 110000 + 1 * 45000, alpha2 + beta1
55000
-
glycosylated beta subunit
60000
-
beta1 subunit, SDS-PAGE, silver staining
7000
-
gamma subunit: 6500-7500 Da, identified in kidney tissue
84000
-
x * 84000, alpha1 isoform, SDS-PAGE