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6.3.5.4: asparagine synthase (glutamine-hydrolysing)

This is an abbreviated version!
For detailed information about asparagine synthase (glutamine-hydrolysing), go to the full flat file.

Word Map on EC 6.3.5.4

Reaction

ATP
+
L-aspartate
+
L-glutamine
+
H2O
=
AMP
+
diphosphate
+
L-asparagine
+
L-glutamate

Synonyms

AS, AS-A, AS-B, AS1, ASN3, AsnA, ASNase, AsnB, ASNS, AsnS1, AsnS2, AsnS3, AsnS4, asparagine amidotransferase, Asparagine synthetase, Asparagine synthetase (glutamine hydrolyzing), Asparagine synthetase (glutamine), Asparagine synthetase (glutamine-hydrolysing), asparagine synthetase 1, asparagine synthetase 2, Asparagine synthetase A, Asparagine synthetase B, asparagine synthetase, glutamine-dependent, asparagine synthetase1, asparagine synthetase2, At5g10240, bacterial type asparagine synthetase A, CaAS1, glutamine-dependent amidotransferase, Glutamine-dependent asparagine synthetase, HvAS1 protein, HvAS2 protein, HvASN1, HvASN2, HvASN3, HvASN4, HvASN5, L-asparaginase, L-Asparagine synthetase, LDBPK_300470, LiAS-A, MLOC_37219, MLOC_44080, MLOC_63089, MLOC_72774, MLOC_75057, More, NAS2, Os03g0291500, Os06g0265000, OsAS1, OsAS2, PVAS1 protein, PVAS2, Ste10, Synthetase, Asn (glutamine), TaASN1, TaASN2, TaASN4, TaSN1, TaSN2, TS11 cell cycle control protein, type -II asparagine synthetase, type I asparagine synthetase, type II asparagine synthetase

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
                6.3.5.4 asparagine synthase (glutamine-hydrolysing)

Substrates Products

Substrates Products on EC 6.3.5.4 - asparagine synthase (glutamine-hydrolysing)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + cysteine sulfinic acid
AMP + diphosphate + cysteine sulfinic acid
show the reaction diagram
-
-
-
?
ATP + L-Asp + L-Gln
AMP + diphosphate + Asn + Glu
show the reaction diagram
ATP + L-Asp + L-Gln
AMP + diphosphate + L-Asn + L-Glu
show the reaction diagram
ATP + L-Asp + L-Gln + H2O
AMP + diphosphate + L-Asn + L-Glu
show the reaction diagram
-
-
-
-
?
ATP + L-Asp + NH2OH
AMP + diphosphate + beta-aspartylhydroxamate
show the reaction diagram
ATP + L-Asp + NH3
AMP + diphosphate + Asn
show the reaction diagram
ATP + L-Asp + NH3
AMP + diphosphate + L-Asn
show the reaction diagram
ATP + L-aspartate + L-glutamine
AMP + diphosphate + L-asparagine + L-glutamate
show the reaction diagram
ATP + L-aspartate + L-glutamine + H2O
AMP + diphosphate + L-asparagine + L-glutamate
show the reaction diagram
ATP + L-aspartate + NH3
AMP + diphosphate + L-asparagine
show the reaction diagram
CTP + L-Asp + L-Gln
CMP + diphosphate + Asn + Glu
show the reaction diagram
-
weak activity
-
-
?
dATP + L-Asp + L-Gln
dAMP + diphosphate + Asn + Glu
show the reaction diagram
-
utilized at a similar rate as ATP
-
-
?
dATP + L-Asp + NH3
dAMP + diphosphate + Asn
show the reaction diagram
-
utilized at a similar rate as ATP
-
-
?
GTP + L-Asp + L-Gln
GMP + diphosphate + Asn + Glu
show the reaction diagram
L-Glutamic acid gamma-monohydroxamate + H2O
Hydroxylamine + Glu
show the reaction diagram
-
-
-
-
?
L-glutamine
L-glutamate + NH3
show the reaction diagram
L-glutamine + H2O
L-glutamate + NH3
show the reaction diagram
UTP + L-Asp + L-Gln
UMP + diphosphate + Asn + Glu
show the reaction diagram
-
weak activity
-
-
?
additional information
?
-