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6.3.4.7: ribose-5-phosphate-ammonia ligase

This is an abbreviated version!
For detailed information about ribose-5-phosphate-ammonia ligase, go to the full flat file.

Reaction

ATP
+
ribose 5-phosphate
+
NH3
=
ADP
+
phosphate
+
5-phosphoribosylamine

Synonyms

5-Phosphoribosylamine synthetase, ammonia-ribose 5-phosphate aminotransferase, Ribose 5-phosphate aminotransferase, Synthetase, phosphoribosylamine

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.7 ribose-5-phosphate-ammonia ligase

Reference

Reference on EC 6.3.4.7 - ribose-5-phosphate-ammonia ligase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Reem, G.H.
Enzymatic synthesis of 5'-phosphoribosylamine from ribose 5-phosphate and ammonia, an alternate first step in purine biosynthesis
J. Biol. Chem.
243
5695-5701
1968
Anas platyrhynchos, Gallus gallus, Pigeon
Manually annotated by BRENDA team
Le Gal, M.L.; de Gal, Y.; Roche, J.; Hedegaard, J.
Purine biosynthesis: enzymatic formation of ribosylamine-5-phosphate from ribose-5-phosphate and ammonia
Biochem. Biophys. Res. Commun.
27
618-624
1967
Escherichia coli
Manually annotated by BRENDA team
Westby, C.A.; Tsai, W.C.
De novo purine synthesis in vegetative cells and myxospores
J. Bacteriol.
117
1099-1107
1974
Myxococcus xanthus, Salmonella enterica subsp. enterica serovar Typhimurium
Manually annotated by BRENDA team
Holmes, E.W.; King, G.L.; Leyva, A.; Singer, S.C.
A purine auxotroph deficient in phosphoribosylpyrophosphate amidotransferase and phosphoribosylpyrophosphate aminotransferase activities with normal activity of ribose-5-phosphate aminotransferase
Proc. Natl. Acad. Sci. USA
73
2458-2461
1976
Cricetulus griseus
Manually annotated by BRENDA team