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6.3.4.17: formate-dihydrofolate ligase

This is an abbreviated version!
For detailed information about formate-dihydrofolate ligase, go to the full flat file.

Reaction

ATP
+
formate
+
dihydrofolate
=
ADP
+
phosphate
+
10-formyldihydrofolate

Synonyms

Dihydrofolate formyltransferase, Formyl dihydrofolate synthase, Formyltransferase, dihydrofolate

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.17 formate-dihydrofolate ligase

Reference

Reference on EC 6.3.4.17 - formate-dihydrofolate ligase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Drake, J.C.; Baram, J.; Allegra, C.J.
Isolation and characterization of a novel dihydrofolate formylating enzyme from human MCF-7 breast cancer cells
Biochem. Pharmacol.
39
615-618
1990
Homo sapiens, Lacticaseibacillus casei
Manually annotated by BRENDA team