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6.3.4.16: carbamoyl-phosphate synthase (ammonia)

This is an abbreviated version!
For detailed information about carbamoyl-phosphate synthase (ammonia), go to the full flat file.

Word Map on EC 6.3.4.16

Reaction

2 ATP +

NH3
+
hydrogencarbonate
=
2 ADP
 +
phosphate
 +
Carbamoyl phosphate

Synonyms

arginine-specific CPS, CarB, carbamate kinase-like carbamoyl phosphate synthetase, carbamate kinase-like carbamoyl-phosphate synthetase, carbamoyl phosphate synthase-1, carbamoyl phosphate synthetase, carbamoyl phosphate synthetase 1, carbamoyl phosphate synthetase I, carbamoyl phosphate synthetase-1, carbamoyl-phosphate synthetase, carbamoyl-phosphate synthetase 1, Carbamoyl-phosphate synthetase I, Carbamoylphosphate synthase, Carbamoylphosphate synthase (ammonia), Carbamoylphosphate synthetase, Carbamoylphosphate synthetase (ammonia), Carbamoylphosphate synthetase I, carbamoylphosphate synthetase-I, Carbamyl phosphate synthase I, carbamyl phosphate synthetase I, carbamyl-phosphate synthetase I, Carbamylphosphate synthetase, carbamylphosphate synthetase 1, Carbamylphosphate synthetase I, carbmoylphosphate synthetase, Carbon-dioxide-ammonia ligase, Carbonate kinase (phosphorylating), CK-like CPS, CPS, CPS 1, CPS I, CPS I-like (ammonia- and N-acetyl-L-glutamate-dependent), CPS-1, CPS-I, CPS1, CPSase, CPSase I, CPSI, EC 2.7.2.5, mitochondrial carbamoylphosphate synthetase I, MS-s, Msm_0361, p165, urea-specific CPS

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.16 carbamoyl-phosphate synthase (ammonia)

Specific Activity

Specific Activity on EC 6.3.4.16 - carbamoyl-phosphate synthase (ammonia)

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.00452
ATP synthetase reverse reaction rate, at pH 8.0 and 37°C
0.014
recombinant enzyme expressed in Schizosaccharomyces pombe
0.077
carbamoyl phosphate synthetase reaction rate, at pH 8.0 and 37°C
0.12
deletion mutant lacking the last 13 residues of the carboxyl end
0.3 - 0.46
-
-
0.4
recombinant enzyme expressed in Escherischia coli
0.43
purified recombinant tagged mutant C1327A
0.47
purified recombinant tagged mutant C1337A
0.86
purified recombinant tagged wild-type enzyme
16
-
value at 37°C and 60°C
additional information
-
-