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6.3.4.15: biotin-[biotin carboxyl-carrier protein] ligase

This is an abbreviated version!
For detailed information about biotin-[biotin carboxyl-carrier protein] ligase, go to the full flat file.

Word Map on EC 6.3.4.15

Reaction

ATP
+
biotin
+
[biotin carboxyl-carrier protein]-L-lysine
=
AMP
+
diphosphate
+
[biotin carboxyl-carrier protein]-N6-biotinyl-L-lysine

Synonyms

Acetyl CoA holocarboxylase synthetase, Acetyl coenzyme A holocarboxylase synthetase, bacterial BirA biotin ligase, biotin acetyl-CoA carboxylase ligase, Biotin holoenzyme synthetase, biotin ligase, biotin protein ligase, Biotin--protein ligase, biotin-protein ligase, Biotin-[acetyl coenzyme A carboxylase] synthetase, Biotin-[acetyl-CoA carboxylase] synthetase, Biotin:apocarboxylase ligase, BirA, BirA protein, BPL, group I biotin protein ligase, HCS, Holocarboxylase synthetase, holocarboxylase synthetase 1, More, STK_15250, Synthetase, biotin-[acetyl coenzyme A carboxylase], yBL

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.4 Other carbon-nitrogen ligases
                6.3.4.15 biotin-[biotin carboxyl-carrier protein] ligase

KM Value

KM Value on EC 6.3.4.15 - biotin-[biotin carboxyl-carrier protein] ligase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0052
apo-[acetyl-CoA:carbon-dioxide ligase (ADP-forming)]
-
pH 8.0, 37°C
0.018 - 5.1
ATP
0.0033
avitag-tagged maltose-binding protein
-
recombinant enzyme
-
0.000026 - 0.26
biotin
0.000424
d-biotin
-
pH 8.0, 37°C
0.0017 - 0.0067
desthiobiotin
0.13
yeast acceptor peptide
-
at 25°C
-
0.12
[Escherichia coli apo-biotin-carboxyl-carrier-protein mutant M136S]-L-lysine
-
pH 8.0, 37°C, wild type enzyme
-
0.011
[Escherichia coli apo-biotin-carboxyl-carrier-protein]-L-lysine
-
pH 8.0, 37°C, wild type enzyme
-
0.03 - 0.101
[Sulfolobus tokodaii apo-biotin-carboxyl-carrier-protein mutant S136M]-lysine
-
0.00044 - 0.00058
[Sulfolobus tokodaii apo-biotin-carboxyl-carrier-protein]-lysine
-
additional information
additional information
-