6.3.4.15: biotin-[biotin carboxyl-carrier protein] ligase

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For detailed information about biotin-[biotin carboxyl-carrier protein] ligase, go to the full flat file.

Reaction

Synonyms

Acetyl CoA holocarboxylase synthetase, Acetyl coenzyme A holocarboxylase synthetase, bacterial BirA biotin ligase, biotin acetyl-CoA carboxylase ligase, Biotin holoenzyme synthetase, biotin ligase, biotin protein ligase, Biotin--protein ligase, biotin-protein ligase, Biotin-[acetyl coenzyme A carboxylase] synthetase, Biotin-[acetyl-CoA carboxylase] synthetase, Biotin:apocarboxylase ligase, BirA, BirA protein, BPL, group I biotin protein ligase, HCS, Holocarboxylase synthetase, holocarboxylase synthetase 1, More, STK_15250, Synthetase, biotin-[acetyl coenzyme A carboxylase], yBL

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.4 Other carbon-nitrogen ligases

                6.3.4.15 biotin-[biotin carboxyl-carrier protein] ligase

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Results	in table
32398	AA Sequence
16	Application
1	CAS Registry Number
38	Cloned(Commentary)
68	Cofactor
14	Crystallization (Commentary)
24	Disease/ Diagnostics
16	General Information
3	IC50 Value
28	Inhibitors
13	kcat/KM [mM/s]
13	Ki Value [mM]
53	KM Value [mM]
10	Localization
30	Metals/Ions
17	Molecular Weight [Da]
52	Natural Substrates/ Products (Substrates)
411	Organism
5	Pathway
94	PDB ID
9	pH Optimum
68	Protein Variants
31	Purification (Commentary)
4	Reaction
3	Reaction Type
99	Reference
15	Source Tissue
4	Specific Activity [micromol/min/mg]
2	Storage Stability
149	Substrates and Products (Substrate)
30	Subunits
140	Synonyms
1	Systematic Name
21	Temperature Optimum [°C]
6	Temperature Stability [°C]
39	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 6.3.4.15 - biotin-[biotin carboxyl-carrier protein] ligase

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IC50 VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0006

5-chloro-3-[4-(4-[5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl]-1H-1,2,3-triazol-1-yl)butyl]-1,3-benzoxazol-2(3H)-one

Staphylococcus aureus

-

pH not specified in the publication, temperature not specified in the publication

744502

0.00009

5-methyl-3-[4-(4-[5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl]-1H-1,2,3-triazol-1-yl)butyl]-1,3-benzoxazol-2(3H)-one

Staphylococcus aureus

-

pH not specified in the publication, temperature not specified in the publication

744502

8.24

MgAMP

Escherichia coli

-

pH 8.0, 37°C

690406