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6.3.3.2: 5-formyltetrahydrofolate cyclo-ligase

This is an abbreviated version!
For detailed information about 5-formyltetrahydrofolate cyclo-ligase, go to the full flat file.

Word Map on EC 6.3.3.2

Reaction

ATP
+
5-formyltetrahydrofolate
=
ADP
+
phosphate
+
5,10-methenyltetrahydrofolate

Synonyms

5,10-methenyl-tetrahydrofolate synthetase, 5,10-Methenyltetrahydrofolate synthetase, 5,10-Methenyltetrahydropteroylglutamate synthetase, 5-CHO-THF cycloligase, 5-FCL, 5-Formyltetrahydrofolate cyclodehydrase, CH+-THF synthetase, Fau1p, Formyltetrahydrofolic cyclodehydrase, Methenyl THFS, Methenyl-THF synthetase, Methenyltetrahydrofolate synthetase, More, MTHFD1, MTHFS, N5-Formyltetrahydrofolic acid cyclodehydrase, Synthetase, methenyltetrahydrofolate, ygfA

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.3 Cyclo-ligases
                6.3.3.2 5-formyltetrahydrofolate cyclo-ligase

Molecular Weight

Molecular Weight on EC 6.3.3.2 - 5-formyltetrahydrofolate cyclo-ligase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
22000
-
monomeric recombinant enzyme, gel filtration
23000
23200
x * 23200, recombinant enzyme, SDS-PAGE
23229
-
x * 23229, calculation from nucleotide sequence
25000
25210
-
calculated from amino acid sequence
25220
-
MALDI-TOF
26500
1 * 26500, recombinant truncated enzyme, amino acid sequence determination
26500 - 29000
-
gel filtration, HPLC gel filtration, equilibrium ultracentrifugation
27000
44000
-
dimeric recombinant enzyme, gel filtration