6.3.2.12: dihydrofolate synthase

This is an abbreviated version!
For detailed information about dihydrofolate synthase, go to the full flat file.

Word Map on EC 6.3.2.12

6.3.2.12

tetrahydrofolate

polyglutamylated

analysis

medicine

drug development

biotechnology

Reaction

Synonyms

7,8-Dihydrofolate synthetase, 7,8-Dihydropteroate:L-glutamate ligase (ADP), DHFR, DHFS, dihydrofolate reductase, dihydrofolate synthase, Dihydrofolate synthetase, dihydrofolate synthetase-folylpolyglutamate synthetase, dihydropteroate:L-glutamate ligase (ADP-forming), FHFS, FHFS/FPGS, FolC, Folylpoly-(gamma-glutamate) synthetase-dihydrofolate synthase, Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase, H2-folate synthetase, LH57_13380, PfDHFS-FPGS, PNEJI1_000945, Rv2447c, Synthetase, dihydrofolate

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.2 Acid—amino-acid ligases (peptide synthases)

6.3.2.12 dihydrofolate synthase

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Results	in table
15632	AA Sequence
8	Application
1	CAS Registry Number
13	Cloned(Commentary)
3	Cofactor
1	Crystallization (Commentary)
1	Expression
11	General Information
2	General Stability
1	IC50 Value
35	Inhibitors
3	Ki Value [mM]
26	KM Value [mM]
9	Localization
38	Metals/Ions
8	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
402	Organism
6	Pathway
5	PDB ID
6	pH Optimum
3	pH Range
60	Protein Variants
12	Purification (Commentary)
1	Reaction
2	Reaction Type
51	Reference
4	Source Tissue
7	Specific Activity [micromol/min/mg]
4	Storage Stability
57	Substrates and Products (Substrate)
4	Subunits
43	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Stability [°C]

Synonyms

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Synonyms on EC 6.3.2.12 - dihydrofolate synthase

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7,8-Dihydrofolate synthetase

7,8-Dihydropteroate:L-glutamate ligase (ADP)

DHFR

3 entries

DHFS

8 entries

dihydrofolate reductase

3 entries

dihydrofolate synthase

Plasmodium falciparum

705610

Dihydrofolate synthetase

dihydrofolate synthetase-folylpolyglutamate synthetase

Plasmodium falciparum

Q9U738

653172

dihydropteroate:L-glutamate ligase (ADP-forming)

FHFS

FHFS/FPGS

FolC

5 entries

Folylpoly-(gamma-glutamate) synthetase-dihydrofolate synthase

Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase

H2-folate synthetase

Plasmodium falciparum

Q9U738

653172

LH57_13380

2 entries

PfDHFS-FPGS

Plasmodium falciparum

bifunctional protein together with folypolyglutamate synthase, EC 6.3.2.17

705610

PNEJI1_000945

2 entries

Rv2447c

2 entries

Synthetase, dihydrofolate