6.3.2.12: dihydrofolate synthase

This is an abbreviated version!
For detailed information about dihydrofolate synthase, go to the full flat file.

Word Map on EC 6.3.2.12

Reaction

ATP
+
7,8-dihydropteroate
+
L-glutamate
=
ADP
+
phosphate
+
7,8-dihydropteroylglutamate

Synonyms

7,8-Dihydrofolate synthetase, 7,8-Dihydropteroate:L-glutamate ligase (ADP), Dihydrofolate synthetase, FHFS, FHFS/FPGS, Folylpoly-(gamma-glutamate) synthetase-dihydrofolate synthase, Folylpoly-gamma-glutamate synthetase-dihydrofolate synthetase, Synthetase, dihydrofolate, DHFR, H2-folate synthetase, dihydrofolate synthetase-folylpolyglutamate synthetase, DHFS, dihydropteroate:L-glutamate ligase (ADP-forming), dihydrofolate reductase, FolC, dihydrofolate synthase, PfDHFS-FPGS, PNEJI1_000945, Rv2447c, LH57_13380

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.2 Acid—amino-acid ligases (peptide synthases)
                6.3.2.12 dihydrofolate synthase

Natural Substrates Products

Natural Substrates Products on EC 6.3.2.12 - dihydrofolate synthase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + 7,8-dihydropteroate + L-Glu
?
show the reaction diagram
-
enzyme of 5,6,7,8-tetrahydropteroyl-Glun synthesis pathway
-
-
?
ATP + 7,8-dihydropteroate + L-glutamate
ADP + phosphate + 7,8-dihydropteroylglutamate
show the reaction diagram