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6.3.1.4: aspartate-ammonia ligase (ADP-forming)

This is an abbreviated version!
For detailed information about aspartate-ammonia ligase (ADP-forming), go to the full flat file.

Reaction

ATP
+
L-aspartate
 +
NH3
=
ADP
 +
phosphate
 +
L-asparagine

Synonyms

Asparagine synthetase, Asparagine synthetase (ADP-forming), Synthetase, asparagine (adenosine diphosphate-forming), Asparagine synthetase (adenosine diphosphate-forming), ASNS

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.1 Acid—ammonia (or amine) ligases (amide synthases)
                6.3.1.4 aspartate-ammonia ligase (ADP-forming)

Natural Substrates Products

Natural Substrates Products on EC 6.3.1.4 - aspartate-ammonia ligase (ADP-forming)

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + L-aspartate + NH3
ADP + phosphate + L-asparagine
show the reaction diagram
-
-
-
-
?
additional information
?
-
-
importance of ASNS protein in the cellular mechanisms that confer drug resistance upon the leukemic cells
-
-
?