6.3.1.4: aspartate-ammonia ligase (ADP-forming)

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For detailed information about aspartate-ammonia ligase (ADP-forming), go to the full flat file.

Reaction

Synonyms

ASNS, Asparagine synthetase, Asparagine synthetase (adenosine diphosphate-forming), Asparagine synthetase (ADP-forming), Synthetase, asparagine (adenosine diphosphate-forming)

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.1 Acid—ammonia (or amine) ligases (amide synthases)

6.3.1.4 aspartate-ammonia ligase (ADP-forming)

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6	Metals/Ions
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Cloned on EC 6.3.1.4 - aspartate-ammonia ligase (ADP-forming)

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expression analysis in HEK-293 cells in response to ATF4 or CHOP

Homo sapiens

693193

quantitative enzyme expression analysis in Hep-G2 cells in absence or presence of UPR blockers and activators, transcription factor recruitment to the ASNS promoter during the UPR, transcriptional activation of UPR target genes is mediated by three signaling cascades PERK/eIF2alpha/ATF4, ATF6, and IRE1/XBP1, UPR activation does not trigger increased recruitment of Mediator subunits to the ASNS promoter, the IRE1/XBP1 and ATF6 branches of the UPR do not participate in the induction of ASNS transcription, overview

Homo sapiens

690840