Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

6.3.1.14: diphthine-ammonia ligase

This is an abbreviated version!
For detailed information about diphthine-ammonia ligase, go to the full flat file.

Reaction

ATP
+
diphthine-[translation elongation factor 2]
+
NH3
=
AMP
+
diphosphate
+
diphthamide-[translation elongation factor 2]

Synonyms

Diphthamide synthase, diphthamide synthetase, DPH6, EC 6.3.2.22, Synthetase, diphthamide, YLR143w

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.1 Acid—ammonia (or amine) ligases (amide synthases)
                6.3.1.14 diphthine-ammonia ligase

Substrates Products

Substrates Products on EC 6.3.1.14 - diphthine-ammonia ligase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + diphthine + ammonia
ADP + phosphate + diphthamide
show the reaction diagram
ATP + diphthine-[peptide 686-VNILDVTLHADAIHR-700] + NH3
AMP + diphosphate + diphthamide-[peptide 686-VNILDVTLHADAIHR-700]
show the reaction diagram
eEF2-derived peptide sequence
-
-
?
ATP + diphthine-[translation elongation factor 2] + NH3
AMP + diphosphate + diphthamide-[translation elongation factor 2]
show the reaction diagram
CTP + diphthine + ammonia
CDP + phosphate + diphthamide
show the reaction diagram
GTP + diphthine + ammonia
GDP + phosphate + diphthamide
show the reaction diagram
additional information
?
-