6.2.1.20: long-chain-fatty-acid-[acyl-carrier-protein] ligase

This is an abbreviated version!
For detailed information about long-chain-fatty-acid-[acyl-carrier-protein] ligase, go to the full flat file.

Reaction

Synonyms

AAE15, AAS, AasC, AasS, ACP synthase, AcpS, ACSL, acyl carrier protein synthase, acyl-ACP synthase, Acyl-ACP synthetase, Acyl-acyl carrier protein synthetase, Acyl-CoA ligase, Acyl-CoA synthetase, Acyl-[acyl carrier protein] synthetase, Acyl-[acyl-carrier-protein]synthetase, At4g14070, CT776, CTO_0846, LipA, PfACP, slr1609, Stearoyl-ACP synthetase, Synthetase, acyl-[acyl carrier protein]

ECTree

     6 Ligases

         6.2 Forming carbon-sulfur bonds

             6.2.1 Acid-thiol ligases

                6.2.1.20 long-chain-fatty-acid-[acyl-carrier-protein] ligase

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Results	in table
3	Activating Compound
2369	AA Sequence
5	Application
2	CAS Registry Number
10	Cloned(Commentary)
7	Cofactor
22	General Information
4	General Stability
6	Inhibitors
24	KM Value [mM]
15	Localization
16	Metals/Ions
6	Molecular Weight [Da]
23	Natural Substrates/ Products (Substrates)
52	Organism
6	Pathway
6	PDB ID
4	pH Optimum
6	Protein Variants
12	Purification (Commentary)
1	Reaction
3	Reaction Type
33	Reference
3	Source Tissue
9	Specific Activity [micromol/min/mg]
3	Storage Stability
97	Substrates and Products (Substrate)
4	Subunits
68	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Stability [°C]
1	Turnover Number [1/s]

KM Value

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KM Value on EC 6.2.1.20 - long-chain-fatty-acid-[acyl-carrier-protein] ligase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.005 - 7.9

acyl-carrier protein

3 entries

0.3 - 2.5

ATP

2 entries

0.1

Decanoic acid

Escherichia coli

-

-

688

0.0035

E. coli acyl-carrier protein

Escherichia coli

-

-

686

0.025

lauric acid

Escherichia coli

-

-

688

0.023

linoleic acid

Rhodotorula glutinis

-

pH 8.0, 30°C

654491

0.015

myristic acid

Escherichia coli

-

palmitic acid

688

0.166

octanoic acid

Escherichia coli

-

-

688

0.01 - 0.03

oleic acid

3 entries

0.0053 - 0.043

palmitic acid

2 entries

0.02

palmitoleic acid

2 entries

0.005 - 0.015

saturated fatty acids

Escherichia coli

-

C12:0 to C16:0

683

-

0.004

spinach acyl-carrier protein

Escherichia coli

-

-

686

0.013 - 0.03

stearic acid

2 entries

0.03 - 0.16

unsaturated fatty acids

Escherichia coli

-

fatty acids with shorter chain length than 12

683

-

additional information

additional information

Vibrio harveyi

-

Km values given for several mutant acyl-carrier proteins

645410

-

0.005

acyl-carrier protein

Escherichia coli

-

-

684

0.016

acyl-carrier protein

Escherichia coli

-

-

685

7.9

acyl-carrier protein

Vibrio harveyi

-

pH 7.8, 37°C

645410

0.3

ATP

Escherichia coli

-

-

684

2.5

ATP

Rhodotorula glutinis

-

pH 8.0, 30°C

654491

0.01

oleic acid

Synechococcus elongatus

Q31PS1

pH 8.0

706328

0.025

oleic acid

Rhodotorula glutinis

-

pH 8.0, 30°C

654491

0.03

oleic acid

Escherichia coli

-

-

684

0.0053

palmitic acid

Escherichia coli

-

-

684

0.043

palmitic acid

Rhodotorula glutinis

-

pH 8.0, 30°C

654491

0.02

palmitoleic acid

Vibrio harveyi

-

E. coli [acyl-carrier protein]

689

0.02

palmitoleic acid

Escherichia coli

-

cis-vaccenic acid, oleic acid, linoleic acid

688

0.013

stearic acid

Escherichia coli

-

-

688

0.03

stearic acid

Rhodotorula glutinis

-

pH 8.0, 30°C

654491