6.2.1.17: propionate-CoA ligase

This is an abbreviated version!
For detailed information about propionate-CoA ligase, go to the full flat file.

Reaction

Synonyms

3-hydroxypropionyl-CoA synthetase, 3-hydroxypropionyl-coenzyme A synthetase, ACSS3, Propionate-CoA synthetase, Propionyl CoA synthetase, Propionyl-CoA synthase, Propionyl-CoA synthetase, Propionyl-coenzyme A synthetase, PrpE, Synthetase, propionyl coenzyme A

ECTree

     6 Ligases

         6.2 Forming carbon-sulfur bonds

             6.2.1 Acid-thiol ligases

                6.2.1.17 propionate-CoA ligase

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Results	in table
1	Activating Compound
6621	AA Sequence
2	Application
2	CAS Registry Number
13	Cloned(Commentary)
8	Cofactor
1	Expression
1	General Stability
13	Inhibitors
1	Ki Value [mM]
62	KM Value [mM]
8	Localization
13	Metals/Ions
14	Molecular Weight [Da]
23	Natural Substrates/ Products (Substrates)
28	Organism
13	Pathway
10	pH Optimum
6	pH Stability
8	Protein Variants
10	Purification (Commentary)
1	Reaction
1	Reaction Type
26	Reference
14	Source Tissue
14	Specific Activity [micromol/min/mg]
2	Storage Stability
98	Substrates and Products (Substrate)
11	Subunits
28	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]
37	Turnover Number [1/s]

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SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

8 - 23

3-hydroxypropanoate

2 entries

12

3-hydroxypropionate

Chloroflexus aurantiacus

Q8VRG6

pH 7.8, 55°C

656038

4.8 - 32

acetate

5 entries

1.1 - 26

Acrylate

6 entries

1.1 - 34

ATP

5 entries

0.87 - 6

Butyrate

5 entries

1 - 42

CoA

5 entries

79

diphosphate

Salmonella enterica

-

pH 7.5, 37°C

654636

5.6

propanoate

Metallosphaera sedula

A4YGR1

pH 8.4, 45°C, coupled spectrophotometric assay

692841

1.2 - 33

propionate

5 entries

78

propionyl-AMP

Salmonella enterica

-

pH 7.5, 37°C

654636

8

3-hydroxypropanoate

Sulfurisphaera tokodaii

-

pH 8.4, 65°C

692841

23

3-hydroxypropanoate

Metallosphaera sedula

A4YGR1

pH 8.4, 65°C

692841

4.8

acetate

Salmonella enterica

-

pH 8.0, 37°C

655578

4.8

acetate

Salmonella enterica

-

45°C, pH 7.0

655578

6.8

acetate

Ralstonia solanacearum

-

pH 8.0, 37°C

655578

6.8

acetate

Ralstonia solanacearum

-

37°C, pH 8.0

655578

32

acetate

Salmonella enterica

-

pH 7.5, 37°C

654636

1.1

Acrylate

Salmonella enterica

-

pH 8.0, 37°C

655578

1.1

Acrylate

Salmonella enterica

-

45°C, pH 7.0

655578

1.3

Acrylate

Ralstonia solanacearum

-

pH 8.0, 37°C

655578

1.3

Acrylate

Ralstonia solanacearum

-

37°C, pH 8.0

655578

5.4

Acrylate

Metallosphaera sedula

A4YGR1

pH 8.4, 45°C, coupled spectrophotometric assay

692841

26

Acrylate

Salmonella enterica

-

pH 7.5, 37°C

654636

1.1

ATP

Salmonella enterica

-

pH 8.0, 37°C

655578

1.1

ATP

Salmonella enterica

-

45°C, pH 7.0: cosubstrate: propanoate

655578

1.5

ATP

Ralstonia solanacearum

-

pH 8.0, 37°C

655578

1.5

ATP

Ralstonia solanacearum

-

37°C, pH 8.0, cosubstrate: propanoate

655578

34

ATP

Salmonella enterica

-

pH 7.5, 37°C

654636

0.87

Butyrate

Salmonella enterica

-

pH 8.0, 37°C

655578

0.87

Butyrate

Salmonella enterica

-

45°C, pH 7.0

655578

1.7

Butyrate

Ralstonia solanacearum

-

pH 8.0, 37°C

655578

1.7

Butyrate

Ralstonia solanacearum

-

37°C, pH 8.0

655578

6

Butyrate

Salmonella enterica

-

pH 7.5, 37°C

654636

1

CoA

Salmonella enterica

-

pH 8.0, 37°C

655578

1

CoA

Salmonella enterica

-

45°C, pH 7.0, cosubstrate: propanoate

655578

2.4

CoA

Ralstonia solanacearum

-

pH 8.0, 37°C

655578

2.4

CoA

Ralstonia solanacearum

-

37°C, pH 8.0, cosubstrate: propanoate

655578

42

CoA

Salmonella enterica

-

pH 7.5, 37°C

654636

1.2

propionate

Salmonella enterica

-

pH 8.0, 37°C

655578

1.2

propionate

Salmonella enterica

-

45°C, pH 7.0

655578

1.8

propionate

Ralstonia solanacearum

-

pH 8.0, 37°C

655578

1.8

propionate

Ralstonia solanacearum

-

37°C, pH 8.0

655578

33

propionate

Salmonella enterica

-

pH 7.5, 37°C

654636