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6.2.1.14: 6-carboxyhexanoate-CoA ligase

This is an abbreviated version!
For detailed information about 6-carboxyhexanoate-CoA ligase, go to the full flat file.

Word Map on EC 6.2.1.14

Reaction

ATP
+
6-Carboxyhexanoate
+
CoA
=
AMP
+
diphosphate
+
6-carboxyhexanoyl-CoA

Synonyms

6-Carboxyhexanoate-CoA synthetase, 6-Carboxyhexanoyl-CoA synthetase, AaBioW, BaBioW, BioW, Pimeloyl-CoA synthase, Pimeloyl-CoA synthetase, Pimelyl-CoA synthetase, Synthetase, pimelyl coenzyme A

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.14 6-carboxyhexanoate-CoA ligase

Reference

Reference on EC 6.2.1.14 - 6-carboxyhexanoate-CoA ligase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Izumi, Y.; Morita, H.; Sato, K.; Tani, Y.; Ogata, K.
Synthesis of biotin-vitamers from pimelic acid and coenzyme A by cell-free extracts of various bacteria
Biochim. Biophys. Acta
264
210-213
1972
Enterobacter cloacae, Priestia megaterium, Bacillus subtilis, Lysinibacillus sphaericus, Kocuria rosea, Pseudomonas fluorescens, Enterobacter cloacae IAM 1221, Pseudomonas fluorescens AKU 0821, Priestia megaterium NIHB 12, Kocuria rosea IFO 3764, Lysinibacillus sphaericus IFO 3525, Bacillus subtilis IAM 1193
Manually annotated by BRENDA team
Izumi, Y.; Morita, H.; Tani, Y.; Ogata, K.
The pimelyl-CoA synthetase responsible for the first step in biotin biosynthesis by microorganisms
Agric. Biol. Chem.
38
2257-2262
1974
Klebsiella aerogenes, Enterobacter cloacae, Priestia megaterium, Bacillus subtilis, Lysinibacillus sphaericus, Escherichia coli, Kocuria rosea, Pseudomonas fluorescens, Devosia riboflavina, Enterobacter cloacae IAM 1221, Pseudomonas fluorescens AKU 0821, Priestia megaterium NIHB 12, Kocuria rosea IFO 3764, Lysinibacillus sphaericus IFO 3525, Kocuria rosea IAM 1257, Bacillus subtilis IAM 1193, Devosia riboflavina IFO 3140
-
Manually annotated by BRENDA team
Baldet, P.; Gerbling, H.; Axiotis, S.; Douce, R.
Biotin biosynthesis in higher plant cells. Identification of intermediates
Eur. J. Biochem.
217
479-485
1993
Lavandula vera
Manually annotated by BRENDA team
Ploux, O.; Soularue, P.; Marquet, A.; Gloeckler, R.; Lemoine, Y.
Investigation of the first step of biotin biosynthesis in Bacillus sphaericus. Purification and characterization of the pimeloyl-CoA synthetase, and uptake of pimelate
Biochem. J.
287
685-690
1992
Lysinibacillus sphaericus, Lysinibacillus sphaericus IFO 3525
Manually annotated by BRENDA team
Gerbling, H.; Axiotis, S.; Douce, R.
A new acyl-CoA synthetase, located in higher plant cytosol
J. Plant Physiol.
143
561-564
1994
Pisum sativum
-
Manually annotated by BRENDA team
Bower, S.; Perkins, J.B.; Yocum, R.R.; Howitt, C.L.; Rahaim, P.; Pero, J.
Cloning, sequencing, and characterization of the Bacillus subtilis biotin biosynthetic operon
J. Bacteriol.
178
4122-4130
1996
Bacillus subtilis, Bacillus subtilis IAM 1193
Manually annotated by BRENDA team
Binieda, A.; Fuhrmann, M.; Lehner, B.; Rey-Berthod, C.; Frutiger-Hughes, S.; Hughes, G.; Shaw, N.M.
Purification, characterization, DNA sequence and cloning of a pimeloyl-CoA synthetase from Pseudomonas mendocina 35
Biochem. J.
340
793-801
1999
Pseudomonas mendocina (Q9ZER2), Pseudomonas mendocina 35 (Q9ZER2)
-
Manually annotated by BRENDA team
Manandhar, M.; Cronan, J.E.
Pimelic acid, the first precursor of the Bacillus subtilis biotin synthesis pathway, exists as the free acid and is assembled by fatty acid synthesis
Mol. Microbiol.
104
595-607
2017
Bacillus subtilis (P53559), Bacillus subtilis, Bacillus subtilis 168 (P53559)
Manually annotated by BRENDA team
Wang, M.; Moynie, L.; Harrison, P.J.; Kelly, V.; Piper, A.; Naismith, J.H.; Campopiano, D.J.
Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters
Nat. Chem. Biol.
13
660-667
2017
Bacillus subtilis (P53559), Bacillus subtilis, Bacillus subtilis 168 (P53559)
Manually annotated by BRENDA team
Estrada, P.; Manandhar, M.; Dong, S.H.; Deveryshetty, J.; Agarwal, V.; Cronan, J.E.; Nair, S.K.
The pimeloyl-CoA synthetase BioW defines a new fold for adenylate-forming enzymes
Nat. Chem. Biol.
13
668-674
2017
Bacillus amyloliquefaciens (E1UV19), Aquifex aeolicus (O67575), Aquifex aeolicus, Bacillus amyloliquefaciens ATCC 23350 / DSM 7 / BCRC 11601 / NBRC 15535 / NRRL B-14393 (E1UV19)
Manually annotated by BRENDA team