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6.2.1.14: 6-carboxyhexanoate-CoA ligase

This is an abbreviated version!
For detailed information about 6-carboxyhexanoate-CoA ligase, go to the full flat file.

Word Map on EC 6.2.1.14

Reaction

ATP
+
6-Carboxyhexanoate
+
CoA
=
AMP
+
diphosphate
+
6-carboxyhexanoyl-CoA

Synonyms

6-Carboxyhexanoate-CoA synthetase, 6-Carboxyhexanoyl-CoA synthetase, AaBioW, BaBioW, BioW, Pimeloyl-CoA synthase, Pimeloyl-CoA synthetase, Pimelyl-CoA synthetase, Synthetase, pimelyl coenzyme A

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.14 6-carboxyhexanoate-CoA ligase

Crystallization

Crystallization on EC 6.2.1.14 - 6-carboxyhexanoate-CoA ligase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
crystal structure determination and analysis of free wild-type AaBioW, selenomethinonine-labeled AaBioW with pimelate, AaBioW with AMP-CPP-Mg2+-pimelate, and AaBioW with CoA-AMP
crystal structure determination and analysis of wild-type enzyme
purified K2PtCl4-pimeloyl-adenylate-diphosphate complex, pimelic acid-CoASH complex, pimeloyl-adenylate-diphosphate, and AMP-PNP-pimelic acid complexes, X-ray diffraction structure determination and analysis at 2.04-2.44 A resolution