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6.2.1.13: acetate-CoA ligase (ADP-forming)

This is an abbreviated version!
For detailed information about acetate-CoA ligase (ADP-forming), go to the full flat file.

Word Map on EC 6.2.1.13

Reaction

ATP
+
acetate
 +
CoA
=
ADP
 +
phosphate
 +
acetyl-CoA

Synonyms

ACD, acetate:CoA ligase [ADP-forming], acetate:coenzyme A ligase (ADP-forming), Acetyl-CoA synthetase, Acetyl-CoA synthetase (ADP-forming), acetyl-coenzyme A synthetase, acetyl-coenzyme A synthetase (ADP-forming), ACS, ACS III, ACS1, ACS2, ADP acetyl-coenzyme A synthetase, ADP-ACS, ADP-forming acetyl-CoA synthetase, ADP-forming acetyl-CoA synthetase isoenzyme I, ADP-forming acetyl-coenzyme A synthetase, ADP-forming acyl coenzyme A synthetase, ADP-forming acyl-CoA synthetase, EhACD, PF1540, PF1787, Synthetase, acetyl coenzyme A (adenosine diphosphate-forming), TK0944/TK0943 protein

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.13 acetate-CoA ligase (ADP-forming)

Turnover Number

Turnover Number on EC 6.2.1.13 - acetate-CoA ligase (ADP-forming)

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TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.18 - 240
acetate
0.12 - 157
acetyl-CoA
0.27 - 203
ADP
0.25 - 320
ATP
0.25 - 328
CoA
21 - 411
GDP
27 - 180
GTP
66
indoleacetate
-
isoenzyme ACS II
22 - 55
Isobutyrate
8 - 121
isobutyryl-CoA
40.6 - 89
phenylacetate
138
phenylacetyl-CoA
-
isoenzyme ACS II
0.22 - 182
phosphate
190
propionate
at pH 7.3 and 37°C
21
propionyl-CoA
at pH 7.3 and 37°C
26.1
thioglycolate
Q5JIA8; Q5JIA9
at pH 6.5 and 55°C