6.2.1.13: acetate-CoA ligase (ADP-forming)
This is an abbreviated version!
For detailed information about acetate-CoA ligase (ADP-forming), go to the full flat file.
Word Map on EC 6.2.1.13
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6.2.1.13
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archaea
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saethre-chotzen
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amitochondriate
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hyperthermophilic
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cranial
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protist
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entamoeba
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giardia
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histolytica
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acrocephalosyndactyly
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amp-forming
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pyrococcus
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furiosus
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succinyl-coa
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skull
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propionyl-coa
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lamblia
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pyruvate:ferredoxin
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sutures
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archaeoglobus
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archaebacteria
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phosphotransacetylase
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acetate-forming
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ppi-dependent
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syndactyly
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embden-meyerhof
- 6.2.1.13
- archaea
-
saethre-chotzen
-
amitochondriate
-
hyperthermophilic
-
cranial
-
protist
-
entamoeba
- giardia
- histolytica
-
acrocephalosyndactyly
-
amp-forming
- pyrococcus
- furiosus
- succinyl-coa
-
skull
- propionyl-coa
- lamblia
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pyruvate:ferredoxin
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sutures
- archaeoglobus
- archaebacteria
- phosphotransacetylase
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acetate-forming
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ppi-dependent
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syndactyly
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embden-meyerhof
Reaction
Synonyms
ACD, acetate:CoA ligase [ADP-forming], acetate:coenzyme A ligase (ADP-forming), Acetyl-CoA synthetase, Acetyl-CoA synthetase (ADP-forming), acetyl-coenzyme A synthetase, acetyl-coenzyme A synthetase (ADP-forming), ACS, ACS III, ACS1, ACS2, ADP acetyl-coenzyme A synthetase, ADP-ACS, ADP-forming acetyl-CoA synthetase, ADP-forming acetyl-CoA synthetase isoenzyme I, ADP-forming acetyl-coenzyme A synthetase, ADP-forming acyl coenzyme A synthetase, ADP-forming acyl-CoA synthetase, EhACD, PF1540, PF1787, Synthetase, acetyl coenzyme A (adenosine diphosphate-forming), TK0944/TK0943 protein
ECTree
6.2.1.13 acetate-CoA ligase (ADP-forming)Advanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 6.2.1.13 - acetate-CoA ligase (ADP-forming)
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
ADP + phosphate + acetyl-CoA
?
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enzyme catalyzes acetate formation and ATP generation during fermentation of pyruvate to acetate
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?
ADP + phosphate + acetyl-CoA
?
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energy-conserving pyruvate-to-acetate pathway
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?
ADP + phosphate + acetyl-CoA
?
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enzyme catalyzes acetate formation and ATP generation during fermentation of pyruvate to acetate
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-
?
ADP + phosphate + acetyl-CoA
ATP + acetate + CoA
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Archaeoglobus fulgidus strain 7324 converts starch to acetate via a modified Embden-Meyerhof pathway and acetyl-CoA synthetase (ADP-forming)
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-
?
ADP + phosphate + acetyl-CoA
ATP + acetate + CoA
the specific activity in the acetate-forming direction is approximately half that observed in the acetyl-CoA-forming direction
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-
r
ADP + phosphate + acetyl-CoA
ATP + acetate + CoA
enzyme catalyzes acetate formation and ATP generation during fermentation of pyruvate to acetate
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?
ADP + phosphate + acetyl-CoA
ATP + acetate + CoA
enzyme catalyzes acetate formation and ATP generation during fermentation of pyruvate to acetate
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?
ADP + phosphate + acetyl-CoA
ATP + acetate + CoA
Giardia intestinalis WB / CC 30957
enzyme catalyzes acetate formation and ATP generation during fermentation of pyruvate to acetate
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?
ADP + phosphate + acetyl-CoA
ATP + acetate + CoA
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downregulation of the enzyme is observed during periods of acetate consumption
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-
?
ADP + phosphate + acetyl-CoA
ATP + acetate + CoA
Q9Y8L0, Q9Y8L1
major energy-conserving reaction during pyruvate and sugar conversion to acetate, catalyzing acetate formation and ATP synthesis
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r
ATP + acetate + CoA
ADP + phosphate + acetyl-CoA
preferred direction of reaction
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-
r
ATP + acetate + CoA
ADP + phosphate + acetyl-CoA
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the enzyme is required for growth on ethanol. ACS activity is induced upon growth on ethanol, 2,3-butanediol, malonate and acetate
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-
?
ATP + acetate + CoA
ADP + phosphate + acetyl-CoA
the enzyme catalyzes the formation of acetate from acetyl-CoA and concomitant ATP synthesis by the mechanism of substrate level phosphorylation
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r
additional information
?
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ADP-forming acetyl-CoA synthetase (ACD) catalyzes the interconversion of acetyl-CoA and acetate
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-
?
additional information
?
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ADP-forming acetyl-CoA synthetase (ACD) catalyzes the interconversion of acetyl-CoA and acetate
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?
additional information
?
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ACS1, encoded by the gene facA, is induced by acetate and repressed by glucose at the transcriptional level
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?
additional information
?
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ACS2 may be a stress protein, expressed under carbon source starvation
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?
