6.2.1.12: 4-coumarate-CoA ligase

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For detailed information about 4-coumarate-CoA ligase, go to the full flat file.

Word Map on EC 6.2.1.12

6.2.1.12

phenylpropanoids

lignin

flavonoid

ammonia-lyase

chalcone

ferulic

4-hydroxylase

p-coumaric

xylem

caffeic

parsley

populus

cinnamate-4-hydroxylase

sinapic

cinnamyl

monolignols

crispum

stilbene

lignification

petroselinum

caffeate

trans-cinnamate

dihydroflavonol

4.3.1.5

taeda

4-reductase

cinnamoylated

elicitor-treated

glycinea

3-o-methyltransferase

3\'-hydroxylase

cinnamoyl-coa

guaiacyl

hydroxycinnamoyl-coas

megasperma

syringyl

ccoaomt

adenylate-forming

biotechnology

synthesis

drug development

Reaction

Synonyms

4-CL, 4-coumarate CoA ligase, 4-coumarate coenzyme A ligase, 4-coumarate/coenzyme A ligase, 4-coumarate: CoA ligase, 4-coumarate: coenzyme A ligase, 4-coumarate:CoA ligase, 4-coumarate:CoA-ligase, 4-coumarate:coenzyme A (CoA) ligase, 4-Coumarate:coenzyme A ligase, 4-coumarate:coenzyme-A ligase-1, 4-coumaroyl CoA ligase, 4-coumaroyl coenzyme A ligase, 4-coumaroyl-CoA ligase, 4-coumaroyl-CoA synthase, 4-coumaroyl:CoA ligase, 4-Coumaryl-CoA synthetase, 4CL, 4CL-A1, 4CL-A2, 4CL-B, 4CL1, 4CL10, 4CL2, 4CL3, 4CL4, 4CL5, 4CL7, Ar4CL, At4CL1, Caffeolyl coenzyme A synthetase, caffeoyl-CoA ligase, caffeoyl-CoA synthetase, caffeoyl-coenzyme A synthetase, CarB, Clone 4CL14, Clone 4CL16, coumarate:CoA ligase, Feruloyl CoA ligase, Feruloyl coenzyme A synthetase, Hc4CL, Hydroxy-cinnamate:CoA ligase, Hydroxycinnamate:CoA ligase, Hydroxycinnamoyl CoA synthetase, LJ4CL1, OB4CL_ctg4, OS4CL, Os4Cl1, Os4Cl2, Os4Cl3, Os4Cl4, Os4Cl5, p-Coumaroyl CoA ligase, p-coumaroyl-CoA ligase, p-Coumaryl coenzyme A synthetase, p-Coumaryl-CoA ligase, p-Coumaryl-CoA synthetase, p-Hydroxycinnamic acid:CoA ligase, p-Hydroxycinnamoyl coenzyme A synthetase, Pc4CL2, Pl4CL1, Pl4CL2, Sa4CL1, Sa4CL2, Sa4CL3, Sinapoyl coenzyme A snthetase, Synthetase, p-coumaroyl coenzyme A, type I 4CL

ECTree

6 Ligases

6.2 Forming carbon-sulfur bonds

6.2.1 Acid-thiol ligases

6.2.1.12 4-coumarate-CoA ligase

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Results	in table
2	Activating Compound
2180	AA Sequence
8	Application
1	CAS Registry Number
62	Cloned(Commentary)
38	Cofactor
2	Crystallization (Commentary)
17	Expression
42	General Information
4	General Stability
2	IC50 Value
47	Inhibitors
68	kcat/KM [mM/s]
4	Ki Value [mM]
279	KM Value [mM]
6	Localization
37	Metals/Ions
26	Molecular Weight [Da]
65	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
145	Organism
28	Pathway
17	PDB ID
26	pH Optimum
5	pH Range
1	pH Stability
5	pI Value
86	Protein Variants
32	Purification (Commentary)
2	Reaction
1	Reaction Type
124	Reference
136	Source Tissue
35	Specific Activity [micromol/min/mg]
9	Storage Stability
390	Substrates and Products (Substrate)
16	Subunits
218	Synonyms
1	Systematic Name
13	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Temperature Stability [°C]
105	Turnover Number [1/s]

pI Value

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pI Value on EC 6.2.1.12 - 4-coumarate-CoA ligase

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5.5

Sorbus aucuparia

D5LLN7, D5LNB5, D5LNB6

sequence calculation

728204

5.6

Sorbus aucuparia

D5LLN7, D5LNB5, D5LNB6

sequence calculation

728204

5.8

Ruta graveolens

B3TJI4, B3TJI5

calculated from amino acid sequence, isozyme 4CL1

6.58

sequence calculation

9.7

Plagiochasma appendiculatum

A0A0D4C3L0

calculated from amino acid sequence

746000