Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

6.2.1.11: biotin-CoA ligase

This is an abbreviated version!
For detailed information about biotin-CoA ligase, go to the full flat file.

Reaction

ATP
+
biotin
+
CoA
=
AMP
+
diphosphate
+
biotinyl-CoA

Synonyms

Biotinyl CoA synthetase, Biotinyl coenzyme A synthetase, Biotinyl-CoA synthetase, Synthetase, biotinyl coenzyme A

ECTree

     6 Ligases
         6.2 Forming carbon-sulfur bonds
             6.2.1 Acid-thiol ligases
                6.2.1.11 biotin-CoA ligase

Substrates Products

Substrates Products on EC 6.2.1.11 - biotin-CoA ligase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
ATP + (+/-)-dethiobiotin + CoA
AMP + diphosphate + dethiobiotinyl-CoA
show the reaction diagram
ATP + 5-(2-thienyl)-n-valerate + CoA
AMP + diphosphate + 5-(2-thienyl)-n-valeryl-CoA
show the reaction diagram
ATP + actithiazic acid + CoA
AMP + diphosphate + actithiazyl-CoA
show the reaction diagram
ATP + alpha-dehydrobiotin + CoA
AMP + diphosphate + alpha-dehydrobiotinyl-CoA
show the reaction diagram
-
27% of the activity relative to biotin
-
-
?
ATP + biotin + CoA
?
show the reaction diagram
-
first enzyme involved in biotin degradation
-
-
?
ATP + biotin + CoA
AMP + diphosphate + biotinyl-CoA
show the reaction diagram
ATP + dethiobiotin + CoA
AMP + diphosphate + dethiobiotinyl-CoA
show the reaction diagram
ATP + n-caprylate + CoA
AMP + diphosphate + n-capryloyl-CoA
show the reaction diagram
-
19% of the activity relative to biotin
-
-
?
ATP + n-decanoate + CoA
AMP + diphosphate + n-decanoyl-CoA
show the reaction diagram
-
14% of the activity relative to biotin
-
-
?
ATP + n-laurate + CoA
AMP + diphosphate + n-lauroyl-CoA
show the reaction diagram
-
11% of the activity relative to biotin
-
-
?