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6.1.1.5: isoleucine-tRNA ligase

This is an abbreviated version!
For detailed information about isoleucine-tRNA ligase, go to the full flat file.

Word Map on EC 6.1.1.5

Reaction

ATP
+
L-isoleucine
+
tRNAIle
=
AMP
+
diphosphate
+
L-isoleucyl-tRNAIle

Synonyms

EcIleRS, IARS2, Ile-tRNA synthetase, IleRS, ileS, ileS1, ileS2, IRS, Isoleucine translase, Isoleucine--tRNA ligase, Isoleucine-transfer RNA ligase, Isoleucine-tRNA synthetase, isoleucyl tRNA synthetase, Isoleucyl-transfer ribonucleate synthetase, Isoleucyl-transfer RNA synthetase, Isoleucyl-tRNA synthetase, mitochondrial isoleucyl-tRNA synthetase, More, mt isoleucyl-tRNA synthetase, mt-IleRS, Mupirocin resistance protein, ScIleRS, SgIleRS, Synthetase, isoleucyl-transfer ribonucleate

ECTree

     6 Ligases
         6.1 Forming carbon-oxygen bonds
             6.1.1 Ligases forming aminoacyl-tRNA and related compounds
                6.1.1.5 isoleucine-tRNA ligase

Source Tissue

Source Tissue on EC 6.1.1.5 - isoleucine-tRNA ligase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
transmitochondrial
Manually annotated by BRENDA team
-
cell line LCC-RK1
Manually annotated by BRENDA team
-
cell line CRL-1781
Manually annotated by BRENDA team
additional information
-
the cytoplasmic isozyme gene is expressed during the erythrocytic stages and is localized in the proper compartment for the bulk of protein synthesis, while the apicoplast isozyme is expressed at low rates in the erythrocytic stage and gets more abundant in later developmental stages, overview
Manually annotated by BRENDA team