6.1.1.22: asparagine-tRNA ligase

This is an abbreviated version!
For detailed information about asparagine-tRNA ligase, go to the full flat file.

Word Map on EC 6.1.1.22

6.1.1.22

aminoacyl-trna

asnrs

aspartyl-trna

malayi

brugia

aminoacylation

amidotransferase

asparaginylation

asp-trnaasn

glutaminyl-trna

gatcabs

filariasis

transamidation

nondiscriminating

glu-trnagln

mischarged

misacylated

asn-trna

nd-asprs

ammonia-dependent

anti-ks

lysyl-trna

trnaasp

histidyl-trna

medicine

drug development

Reaction

Synonyms

AS-AR, AsnRS, Asparagine synthetase A, Asparagine translase, asparagine tRNA synthetase, Asparagine--tRNA ligase, Asparaginyl transfer ribonucleic acid synthetase, Asparaginyl transfer RNA synthetase, asparaginyl tRNA synthetase, Asparaginyl-transfer ribonucleate synthetase, asparaginyl-transfer RNA synthetase, Asparaginyl-tRNA synthetase, Asparagyl-transfer RNA synthetase, class IIb asparaginyl-tRNA synthetase, More, NARS, NARS2, NRS, Potentially protective 63 kDa antigen, PYRAB02460, Synthetase, asparaginyl-transfer ribonucleate

ECTree

6 Ligases

6.1 Forming carbon-oxygen bonds

6.1.1 Ligases forming aminoacyl-tRNA and related compounds

6.1.1.22 asparagine-tRNA ligase

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Results	in table
2	Activating Compound
26248	AA Sequence
3	Application
1	CAS Registry Number
13	Cloned(Commentary)
17	Cofactor
9	Crystallization (Commentary)
127	Disease/ Diagnostics
2	Expression
5	General Information
1	General Stability
13	IC50 Value
49	Inhibitors
4	kcat/KM [mM/s]
36	KM Value [mM]
9	Localization
10	Metals/Ions
16	Molecular Weight [Da]
16	Natural Substrates/ Products (Substrates)
126	Organism
4	Pathway
21	PDB ID
2	pH Optimum
1	pH Range
1	pI Value
15	Protein Variants
13	Purification (Commentary)
3	Reaction
11	Reaction Type
38	Reference
1	Renatured (Commentary)
18	Source Tissue
5	Specific Activity [micromol/min/mg]
2	Storage Stability
53	Substrates and Products (Substrate)
17	Subunits
102	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
3	Temperature Range [°C]
8	Temperature Stability [°C]
29	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 6.1.1.22 - asparagine-tRNA ligase

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0.0017 - 0.0045

asparaginyl sulfamoyl adenylate

2 entries

0.4

human angiotensinogen

Homo sapiens

675081

0.004

L-aspartate-beta-hydroxamate adenylate

Brugia malayi

675081

0.173 - 0.5

LCM01

2 entries

0.123 - 1

LCM02

2 entries

0.05 - 0.065

NSC114691

2 entries

0.025

NSC363624

Brugia malayi

675081

0.24

rishirilide B

Brugia malayi

675081

0.03

tirandamycin G

Brugia malayi

pH and temperature not specified in the publication

716420