6.1.1.19: arginine-tRNA ligase

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For detailed information about arginine-tRNA ligase, go to the full flat file.

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Synonyms

Arg-tRNA synthetase, Arginine translase, Arginine--tRNA ligase, Arginine-tRNA synthetase, Arginyl transfer ribonucleic acid synthetase, Arginyl-transfer RNA synthetase, Arginyl-tRNA synthetase, arginyl�tRNA synthetase, ArgRS, ArgS2, MtArgRS, RARS, RARS2, RRS, Synthetase, arginyl-transfer ribonucleate

ECTree

     6 Ligases

         6.1 Forming carbon-oxygen bonds

             6.1.1 Ligases forming aminoacyl-tRNA and related compounds

                6.1.1.19 arginine-tRNA ligase

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Results	in table
7	Activating Compound
54070	AA Sequence
1	CAS Registry Number
28	Cloned(Commentary)
26	Cofactor
12	Crystallization (Commentary)
122	Disease/ Diagnostics
3	Expression
4	General Information
8	General Stability
2	IC50 Value
34	Inhibitors
12	kcat/KM [mM/s]
2	Ki Value [mM]
132	KM Value [mM]
9	Localization
15	Metals/Ions
30	Molecular Weight [Da]
24	Natural Substrates/ Products (Substrates)
291	Organism
4	Pathway
28	PDB ID
9	pH Optimum
1	pH Range
2	pI Value
2	Posttranslational Modification
33	Protein Variants
38	Purification (Commentary)
9	Reaction
8	Reaction Type
85	Reference
21	Source Tissue
21	Specific Activity [micromol/min/mg]
4	Storage Stability
103	Substrates and Products (Substrate)
26	Subunits
63	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
3	Temperature Range [°C]
8	Temperature Stability [°C]
42	Turnover Number [1/s]

Expression

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Expression on EC 6.1.1.19 - arginine-tRNA ligase

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EXPRESSION

ORGANISM

UNIPROT

LITERATURE

at 24 h, the expression levels of enzyme protein and mRNA in ischemic penumbral tissues are lower than those in normal tissue

Rattus norvegicus

P40329

745485

ischemic preconditioning can inhibit the increased enzyme activity and down-regulate enzyme expression of ischemia-insulted neurons

Rattus norvegicus

P40329

745486

prolonged ischemia insult can induce an escalating activity of the enzyme and leads to enzyme over-expression in primary cultured neurons

Rattus norvegicus

P40329

745486