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5.6.1.1: microtubule-severing ATPase

This is an abbreviated version!
For detailed information about microtubule-severing ATPase, go to the full flat file.

Word Map on EC 5.6.1.1

Reaction

n ATP + n H2O +

a microtubule
= n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers

Synonyms

adseverin, Arabidopsis thaliana katanin small subunit, AtKSS, D-spastin, DGL1, Dm-Kat60, Drosophila katanin Dm-Kat60, EC 3.6.4.3, kananin, Kat60, katanin, KATANIN 1, katanin p60, katanin p60 ATPase-containing subunit A1, katanin p60 microtubule-severing protein, KATNAL1, kinesin spindle protein, kp60-NTD, KSP, mei-1, MEI-1/MEI-2 complex, MEI-1/MEI-2 katanin complex, microtuble severing AAA ATPase spastin, microtuble-severing AAA ATPase, microtuble-severing ATPase spastin, microtubule severing protein, microtubule-severing AAA ATPase, microtubule-severing ATPase, microtubule-severing complex katanin, microtubule-severing complex MEI-1/MEI-2 katanin, microtubule-severing protein, microtubule-stimulated ATPase, MT-severing AAA ATPase, P60, p60 KAT1p, p60 katanin, P60-kananin, P60-katanin, p81-p60, Pf15, plant microtubule-severing protein, rice KTN1, scinderin, SPAS-1, spastin, spastin AAA domain, SPG4, Sug1p, vertebrate katanin

ECTree

     5 Isomerases
         5.6 Isomerases altering macromolecular conformation
             5.6.1 Enzymes altering polypeptide conformation or assembly
                5.6.1.1 microtubule-severing ATPase

Molecular Weight

Molecular Weight on EC 5.6.1.1 - microtubule-severing ATPase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
28000
GST-AtKSS1, determined by SDS-PAGE
350000
-
hexamer, GST-free spastin, determined by gel filtration analysis and Western blotting
44000
-
full-length spastin without tag, determined by SDS-PAGE
46000
GST-AtKSS2, determined by SDS-PAGE
50000
52000
530000
-
hexamer, GST-spastin, determined by gel filtration analysis and Western blotting
54400
55000
57000
-
SPAS-1L, consists of nine exons, determined by SDS-PAGE and Western blotting
58000
60100
-
theoretical value, calculated from amino acid sequence
62000
62200
spastin isoform: 1st ATG, predicted molecular weight of the isoform tagged with His6
63600
66000
GST-AtKSS13, determined by SDS-PAGE
67200
isoform, first ATG, + exon 4
68000
-
Western blotting, isoform M1
69000
-
GST-spastin, determined by SDS-PAGE
80000
81000
82000
GST-AtKSS23, determined by SDS-PAGE
84000
x * 84000, deduced from genen sequence
85000
-
fusion protein: p60 plant homolog-RFP, SDS-PAGE, Western blot
88000
-
monomer, GST-spastin, determined by gel filtration analysis and Western blotting
95000
-
GST-spastin analyzed on a 12%-PAG