5.4.2.8: phosphomannomutase

This is an abbreviated version!
For detailed information about phosphomannomutase, go to the full flat file.

Reaction

Synonyms

alpha-D-phosphohexomutase, alpha-phosphomannomutase1, EC 2.7.5.7, IMP-sensitive glucose-1,6-bisphosphatase, ManB, ORF17, PGM/PMM, PGM2, PgmG, phosphoglucomutase/phosphomannomutase, Phosphohexomutase, phosphomannomutase, phosphomannomutase 1, phosphomannomutase 2, phosphomannomutase/phosphoglucomutase, phosphomannomutase2, Phosphomannose mutase, Phosphomutase, mannose, PMM, PMM-1, PMM-2, PMM-A1, PMM-A2, PMM-B1, PMM-B2, PMM-D1, PMM-D2, PMM/PGM, PMM1, PMM2, PMMH-22, SP-2, SSO0207

ECTree

     5 Isomerases

         5.4 Intramolecular transferases

             5.4.2 Phosphotransferases (phosphomutases)

                5.4.2.8 phosphomannomutase

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Results	in table
36	Activating Compound
13631	AA Sequence
5	Application
1	CAS Registry Number
38	Cloned(Commentary)
9	Crystallization (Commentary)
704	Disease/ Diagnostics
1	Expression
12	General Information
2	General Stability
2	IC50 Value
35	Inhibitors
2	kcat/KM [mM/s]
74	KM Value [mM]
5	Localization
26	Metals/Ions
19	Molecular Weight [Da]
30	Natural Substrates/ Products (Substrates)
126	Organism
12	Pathway
58	PDB ID
19	pH Optimum
6	pH Range
1	pH Stability
2	pI Value
4	Posttranslational Modification
67	Protein Variants
29	Purification (Commentary)
6	Reaction
7	Reaction Type
80	Reference
21	Source Tissue
15	Specific Activity [micromol/min/mg]
3	Storage Stability
125	Substrates and Products (Substrate)
19	Subunits
104	Synonyms
1	Systematic Name
15	Temperature Optimum [°C]
4	Temperature Range [°C]
6	Temperature Stability [°C]
23	Turnover Number [1/s]

pH Range

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pH Range on EC 5.4.2.8 - phosphomannomutase

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

3 - 9

Acinetobacter haemolyticus

-

about 3% activity at pH 3.0-4.0, about 10% activity at pH 5.0, about 80% activity at pH 6.0, 100% activity at pH 7.5, about 30% activity at pH 8.0, about 10% activity at pH 9.0

748602

4 - 8

Trypanosoma brucei

F4NCC2

activity range, inactive above and below

728329

5.5 - 7.6

Cassia corymbosa

-

50% of maximal activity at pH 5.5 and at pH 7.6

3288

7 - 9

Sphingobium chungbukense

-

-

692918

7.1

Homo sapiens

-

80% of maximal activity

649661

7.5 - 10

Pyrococcus horikoshii

-

-

662065