5.3.1.9: glucose-6-phosphate isomerase

This is an abbreviated version!
For detailed information about glucose-6-phosphate isomerase, go to the full flat file.

Reaction

Synonyms

6-Phosphoglucose isomerase, AfcPGI, AMF, AMF/PGI, At4g24620, autocrine motility factor, autocrine motility factor/phosphoglucose isomerase, Cupin-PGI, D-Glucose-6-phosphate isomerase, D-glucose-6-phosphate ketol-isomerase, G6-PI, Glucose 6-phosphate isomerase, Glucose phosphate isomerase, Glucose phosphoisomerase, glucose-6-phosphate isomerase, glucose-6-phosphate isomerase, cytosolic, Glucosephosphate isomerase 2, GPI, Hexose 6-phosphate isomerase, Hexose isomerase, Hexose monophosphate isomerase, Hexose phosphate isomerase, Hexosephosphate isomerase, Isomerase, glucose phosphate, Neuroleukin, NLK, Oxoisomerase, PGI, PGI/AMF, Pgi1, PGI2, PGI3, pgiA, PHI, Phosphoglucoisomerase, Phosphoglucose isomerase, phosphoglucose isomerase/autocrine motility factor, Phosphohexoisomerase, Phosphohexomutase, Phosphohexose isomerase, Phosphosaccharomutase, SA-36, Sperm antigen-36, SwoM, TK1111, VEG54, Vegetative protein 54

ECTree

     5 Isomerases

         5.3 Intramolecular oxidoreductases

             5.3.1 Interconverting aldoses and ketoses, and related compounds

                5.3.1.9 glucose-6-phosphate isomerase

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Results	in table
1	Activating Compound
49706	AA Sequence
14	Application
1	CAS Registry Number
33	Cloned(Commentary)
25	Crystallization (Commentary)
2172	Disease/ Diagnostics
4	Expression
26	General Information
3	General Stability
4	IC50 Value
151	Inhibitors
37	kcat/KM [mM/s]
42	Ki Value [mM]
180	KM Value [mM]
26	Localization
21	Metals/Ions
105	Molecular Weight [Da]
33	Natural Substrates/ Products (Substrates)
547	Organism
1	Oxidation Stability
34	Pathway
183	PDB ID
38	pH Optimum
8	pH Range
4	pH Stability
2	pI Value
1	Posttranslational Modification
69	Protein Variants
62	Purification (Commentary)
7	Reaction
3	Reaction Type
154	Reference
3	Renatured (Commentary)
69	Source Tissue
37	Specific Activity [micromol/min/mg]
7	Storage Stability
146	Substrates and Products (Substrate)
69	Subunits
110	Synonyms
1	Systematic Name
24	Temperature Optimum [°C]
6	Temperature Range [°C]
47	Temperature Stability [°C]
74	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 5.3.1.9 - glucose-6-phosphate isomerase

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ACTIVATING COMPOUND

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

Zn2+

Pyrococcus furiosus

-

the coordination shell of Zn2+ changes significantly from the initial static crystal conformation to the equilibrated state of the enzyme-D-fructose 6-phosphate complex. Although Zn2+ is not directly involved in the reaction, the metal ion as a structural anchor constructs a hydrogen bond wire to connect the substrate to the outer region, providing a potential channel for hydrogen exchange between the substrate and solvent

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